Table 2.

Summary of emergency indications for transfusion11,15 

IndicationComment
Acute anemia Simple transfusion to baseline Hb 
Acute ischemic stroke Exchange transfusion 
Acute pain Not currently indicated unless additional complication 
Acute chest syndrome No transfusion, simple or exchange transfusion depending on severity 
Acute priapism Consider simple or exchange transfusion if no response to initial treatment 
Multiorgan failure, acute sickle hepatopathy, severe sepsis Exchange transfusion 
IndicationComment
Acute anemia Simple transfusion to baseline Hb 
Acute ischemic stroke Exchange transfusion 
Acute pain Not currently indicated unless additional complication 
Acute chest syndrome No transfusion, simple or exchange transfusion depending on severity 
Acute priapism Consider simple or exchange transfusion if no response to initial treatment 
Multiorgan failure, acute sickle hepatopathy, severe sepsis Exchange transfusion 

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