Table 2.

Incidence and patterns of treatment failure in patients among treatment approaches in early-stage FL

RT alone, n = 171Systemic therapy,* n = 60Systemic therapy + maintenance rituximab, n = 49
n/N%n/N%n/N%P
Total relapses 42/171 24.6 11/60 18.3 2/49 4.1 .006 
In-field relapse only 3/171 1.7 3/60 5.0 0/49 .254 
In-field and distant relapse 4/171 2.3 2/60 3.3 0/49 
Distant relapse only 35/171 20.4 6/60 10.0 2/49 4.1 
Transformation 11/171 6.4 2/60 3.3 0/49 .145 
Lymphoma-related mortality 6/171 3.5 2/60 3.3 2/49 4.1 .694 
All-cause mortality 12 /171 7.0 3/60 5.0 2/49 4.1 .976 
RT alone, n = 171Systemic therapy,* n = 60Systemic therapy + maintenance rituximab, n = 49
n/N%n/N%n/N%P
Total relapses 42/171 24.6 11/60 18.3 2/49 4.1 .006 
In-field relapse only 3/171 1.7 3/60 5.0 0/49 .254 
In-field and distant relapse 4/171 2.3 2/60 3.3 0/49 
Distant relapse only 35/171 20.4 6/60 10.0 2/49 4.1 
Transformation 11/171 6.4 2/60 3.3 0/49 .145 
Lymphoma-related mortality 6/171 3.5 2/60 3.3 2/49 4.1 .694 
All-cause mortality 12 /171 7.0 3/60 5.0 2/49 4.1 .976 
*

Systemic therapy includes immunochemotherapy and CMT.

Includes patients treated with systemic therapy only who relapsed at the site of initial disease.

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