Amplifications in H2ax−/−p53−/−Rag2−/− and H2ax−/−p53−/− tumors
| Chromosome . | H2ax−/−p53−/−Rag2−/− . | H2ax−/−p53−/− . |
|---|---|---|
| 1 | 38.267; 65.0898; 139.054 156.296 165.662; 191.289 | 62.5634; 86.2722; 133.54 135.252; 157.421 |
| 2 | 69.1264* | 25.464; 69.1264*;131.229 |
| 3 | 89.8208*; 93.146; 100.366*; 116.962 | 89.8208*; 100.366* |
| 4 | 122.896 | 63.5489 |
| 5 | 89.8831 | 32.8917; 113.108 |
| 6 | — | 60.4895; 129.194 |
| 7 | 68.3727* | 68.3727* |
| 8 | 21.2231* | 20.9709; 21.2231*; 32.6539 41.2879 |
| 9 | 7.176; 95.8029 | 57.3211; 67.189 |
| 10 | 31.1166 | — |
| 11 | 52.048; 75.2091; 95.2424 | 30.8277; 77.9023; 81.183 82.5368; 94.0043 |
| 12 | 53.7025 | 103.291 |
| 13 | 79.6935 | 62.4982; 82.6848; 90.1354 108.685 |
| 14 | — | 10.0549; 69.8421 |
| 15 | 33.646; 79.1787; 101.059 | 58.3441; 59.5153 |
| 16 | — | 10.9474 |
| 17 | 41.7517 | 79.9512 |
| 18 | 12.1999* | 12.1999*; 37.7442 |
| 19 | 3.654* | 3.654*; 10.7128; 46.1043 |
| X | 119.756*; 149.366 | 119.756* |
| Chromosome . | H2ax−/−p53−/−Rag2−/− . | H2ax−/−p53−/− . |
|---|---|---|
| 1 | 38.267; 65.0898; 139.054 156.296 165.662; 191.289 | 62.5634; 86.2722; 133.54 135.252; 157.421 |
| 2 | 69.1264* | 25.464; 69.1264*;131.229 |
| 3 | 89.8208*; 93.146; 100.366*; 116.962 | 89.8208*; 100.366* |
| 4 | 122.896 | 63.5489 |
| 5 | 89.8831 | 32.8917; 113.108 |
| 6 | — | 60.4895; 129.194 |
| 7 | 68.3727* | 68.3727* |
| 8 | 21.2231* | 20.9709; 21.2231*; 32.6539 41.2879 |
| 9 | 7.176; 95.8029 | 57.3211; 67.189 |
| 10 | 31.1166 | — |
| 11 | 52.048; 75.2091; 95.2424 | 30.8277; 77.9023; 81.183 82.5368; 94.0043 |
| 12 | 53.7025 | 103.291 |
| 13 | 79.6935 | 62.4982; 82.6848; 90.1354 108.685 |
| 14 | — | 10.0549; 69.8421 |
| 15 | 33.646; 79.1787; 101.059 | 58.3441; 59.5153 |
| 16 | — | 10.9474 |
| 17 | 41.7517 | 79.9512 |
| 18 | 12.1999* | 12.1999*; 37.7442 |
| 19 | 3.654* | 3.654*; 10.7128; 46.1043 |
| X | 119.756*; 149.366 | 119.756* |
Data are the subchromosomal regions (in Mb) that exhibit a 4-fold or greater gain in at least 4 or 5 tumors of each genotype.
indicates regions that are common to both genotypes; and —, no genomic amplidications or deletions on those chromosomes found among the tumors.