Association of patient LBP tagSNP genotypes with GN bacteremia
| TagSNP . | All participants (97 cases; 204 controls) . | Whites only (85 cases; 189 controls) . | ||||||
|---|---|---|---|---|---|---|---|---|
| Allele frequencies . | Odds ratio (95% CI) . | P . | Allele frequencies . | Odds ratio (95% CI) . | P . | |||
| Case . | Control . | Case . | Control . | |||||
| 6878 (C/T) | 0.26 | 0.15 | 2.22 (1.39-3.56) | .001 | 0.27 | 0.16 | 2.15 (1.31-3.52) | .002 |
| 17002 (A/G) | 0.40 | 0.50 | 0.65 (0.44-0.95) | .027 | 0.41 | 0.49 | 0.7 (0.47-1.06) | .089 |
| 541 (C/T) | 0.34 | 0.32 | 0.93 (0.63-1.38) | .729 | 0.32 | 0.34 | 0.9 (0.6-1.35) | .602 |
| TagSNP . | All participants (97 cases; 204 controls) . | Whites only (85 cases; 189 controls) . | ||||||
|---|---|---|---|---|---|---|---|---|
| Allele frequencies . | Odds ratio (95% CI) . | P . | Allele frequencies . | Odds ratio (95% CI) . | P . | |||
| Case . | Control . | Case . | Control . | |||||
| 6878 (C/T) | 0.26 | 0.15 | 2.22 (1.39-3.56) | .001 | 0.27 | 0.16 | 2.15 (1.31-3.52) | .002 |
| 17002 (A/G) | 0.40 | 0.50 | 0.65 (0.44-0.95) | .027 | 0.41 | 0.49 | 0.7 (0.47-1.06) | .089 |
| 541 (C/T) | 0.34 | 0.32 | 0.93 (0.63-1.38) | .729 | 0.32 | 0.34 | 0.9 (0.6-1.35) | .602 |
Each tagSNP was analyzed in independent multivariate models that included sex match, disease risk, TBI dose, CMV serostatus, presence of neutropenia pretransplant, recurrent neutropenia after engraftment, and presence of acute or chronic GVHD as covariates.