Nonhematologic adverse events suspected to be related to nilotinib
| Adverse event (N=119 patients) . | All grades, %* . | Grade 3/4, % . |
|---|---|---|
| Rash | 22 | 0 |
| Pruritus | 20 | 0 |
| Constipation | 11 | 0 |
| Headache | 10 | 1 |
| Fatigue | 10 | 1 |
| Nausea | 10 | 1 |
| Diarrhea | 9 | 1 |
| Muscle spasms | 9 | 0 |
| Myalgia | 9 | 1 |
| Alopecia | 8 | 0 |
| Pyrexia | 8 | 1 |
| Abdominal pain | 7 | 1 |
| Anorexia | 6 | 0 |
| Arthralgia | 5 | 0 |
| Peripheral edema | 5 | 0 |
| Upper abdominal pain | 5 | 0 |
| Pain in extremity | 5 | 0 |
| Adverse event (N=119 patients) . | All grades, %* . | Grade 3/4, % . |
|---|---|---|
| Rash | 22 | 0 |
| Pruritus | 20 | 0 |
| Constipation | 11 | 0 |
| Headache | 10 | 1 |
| Fatigue | 10 | 1 |
| Nausea | 10 | 1 |
| Diarrhea | 9 | 1 |
| Muscle spasms | 9 | 0 |
| Myalgia | 9 | 1 |
| Alopecia | 8 | 0 |
| Pyrexia | 8 | 1 |
| Abdominal pain | 7 | 1 |
| Anorexia | 6 | 0 |
| Arthralgia | 5 | 0 |
| Peripheral edema | 5 | 0 |
| Upper abdominal pain | 5 | 0 |
| Pain in extremity | 5 | 0 |
All grades are reported where the frequency was greater than 5%.