Table 2

Hemodynamic parameters in TNF-α–primed sickle mice treated with IVIG

Sickle mouse generationTreatmentMice, no.Venules, no.Venular diameter, μMCenterline velocity, μM/secShear rate, s−1
BMT PBS 68 20.0 ± 0.2 1117 ± 53*** 595 ± 31*** 
BMT Albumin 45 19.8 ± 0.2 1488 ± 118 797 ± 63 
BMT IVIG 55 19.9 ± 0.3 2162 ± 221* 1147 ± 116* 
Parental PBS 20 19.9 ± 0.3 1202 ± 68** 648 ± 17** 
Parental IVIG 31 20.5 ± 0.5 2294 ± 39 1179 ± 30 
Sickle mouse generationTreatmentMice, no.Venules, no.Venular diameter, μMCenterline velocity, μM/secShear rate, s−1
BMT PBS 68 20.0 ± 0.2 1117 ± 53*** 595 ± 31*** 
BMT Albumin 45 19.8 ± 0.2 1488 ± 118 797 ± 63 
BMT IVIG 55 19.9 ± 0.3 2162 ± 221* 1147 ± 116* 
Parental PBS 20 19.9 ± 0.3 1202 ± 68** 648 ± 17** 
Parental IVIG 31 20.5 ± 0.5 2294 ± 39 1179 ± 30 

Data are presented as mean (± SEM).

*

P < .05 compared with albumin.

**

P < .01 compared with PBS control.

***

P < .001 compared with PBS control.

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