Hemodynamic parameters in TNF-α–primed sickle mice treated with IVIG
Sickle mouse generation . | Treatment . | Mice, no. . | Venules, no. . | Venular diameter, μM . | Centerline velocity, μM/sec . | Shear rate, s−1 . |
---|---|---|---|---|---|---|
BMT | PBS | 7 | 68 | 20.0 ± 0.2 | 1117 ± 53*** | 595 ± 31*** |
BMT | Albumin | 4 | 45 | 19.8 ± 0.2 | 1488 ± 118 | 797 ± 63 |
BMT | IVIG | 5 | 55 | 19.9 ± 0.3 | 2162 ± 221* | 1147 ± 116* |
Parental | PBS | 2 | 20 | 19.9 ± 0.3 | 1202 ± 68** | 648 ± 17** |
Parental | IVIG | 2 | 31 | 20.5 ± 0.5 | 2294 ± 39 | 1179 ± 30 |
Sickle mouse generation . | Treatment . | Mice, no. . | Venules, no. . | Venular diameter, μM . | Centerline velocity, μM/sec . | Shear rate, s−1 . |
---|---|---|---|---|---|---|
BMT | PBS | 7 | 68 | 20.0 ± 0.2 | 1117 ± 53*** | 595 ± 31*** |
BMT | Albumin | 4 | 45 | 19.8 ± 0.2 | 1488 ± 118 | 797 ± 63 |
BMT | IVIG | 5 | 55 | 19.9 ± 0.3 | 2162 ± 221* | 1147 ± 116* |
Parental | PBS | 2 | 20 | 19.9 ± 0.3 | 1202 ± 68** | 648 ± 17** |
Parental | IVIG | 2 | 31 | 20.5 ± 0.5 | 2294 ± 39 | 1179 ± 30 |