Characterization of clinical features of 399 ALL cases
| . | Cases, no. (%) . |
|---|---|
| Sex | |
| Male | 230 (57) |
| Female | 169 (43) |
| Age | |
| 1 to 9 yrs | 307 (77) |
| Older than 10 yrs | 92 (23) |
| WBC | |
| Below 102×109/L | 362 (91) |
| Over 102×109/L | 37 (9) |
| Immunophenotype | |
| T-cell | 49 (12) |
| B-cell | 339 (85) |
| Unknown | 11 (3) |
| CNS involvement | |
| Yes | 11 (3) |
| No | 358 (90) |
| unknown | 30 (7) |
| BCR/ABL | |
| Yes | 6 (2) |
| No | 379 (95) |
| Unknown | 14 (3) |
| ETV6/RUNX1 | |
| Yes | 96 (24) |
| No | 270 (68) |
| Unknown | 33 (8) |
| PDN response | |
| Good | 360 (90) |
| Poor | 35 (9) |
| Unknown | 4 (1) |
| . | Cases, no. (%) . |
|---|---|
| Sex | |
| Male | 230 (57) |
| Female | 169 (43) |
| Age | |
| 1 to 9 yrs | 307 (77) |
| Older than 10 yrs | 92 (23) |
| WBC | |
| Below 102×109/L | 362 (91) |
| Over 102×109/L | 37 (9) |
| Immunophenotype | |
| T-cell | 49 (12) |
| B-cell | 339 (85) |
| Unknown | 11 (3) |
| CNS involvement | |
| Yes | 11 (3) |
| No | 358 (90) |
| unknown | 30 (7) |
| BCR/ABL | |
| Yes | 6 (2) |
| No | 379 (95) |
| Unknown | 14 (3) |
| ETV6/RUNX1 | |
| Yes | 96 (24) |
| No | 270 (68) |
| Unknown | 33 (8) |
| PDN response | |
| Good | 360 (90) |
| Poor | 35 (9) |
| Unknown | 4 (1) |
WBC indicates white blood cell count (× 109/L) in peripheral blood at diagnosis; CNS involvement, central nervous system involvement at diagnosis; BCR/ABL and ETV6/RUNX1, BCR/ABL or ETV6/RUNX1 fusion was examined by RT-PCR and/or FISH analysis; PDN, prednisone; and PDN response, blast cell count was 1000/μL or greater in peripheral blood after a 7-day exposure to prednisone and one intrathecal dose of methotrexate.