Significant (P < .05) correlation coefficients among morphologic criteria
| . | WHO diagnosis . | Reticulin grade . | Overall cellularity . | Erythroid cellularity . | Granulocyte cellularity . | Mega cellularity . | Staghorn megas . | Cloudlike megas . | Dysplastic megas . | Pyknotic megas . | Bare mega nuclei . | Mega size . | Cluster numbers . | Cluster type . | Cluster size . | Paratrabec megas . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WHO diagnosis | 1.0 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Reticulin grade | 0.7 | 1.0 | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Overall cellularity | 0.3 | 0.3 | 1.0 | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Erythroid cellularity | NS | NS | 0.3 | 1.0 | — | — | — | — | — | — | — | — | — | — | — | — |
| Granulocyte cellularity | 0.2 | 0.3 | 0.6 | 0.2 | 1.0 | — | — | — | — | — | — | — | — | — | — | — |
| Mega cellularity | 0.3 | 0.3 | 0.5 | 0.2 | 0.4 | 1.0 | — | — | — | — | — | — | — | — | — | — |
| Staghorn megas | −0.3 | NS | NS | 0.1 | NS | 0.1 | 1.0 | — | — | — | — | — | — | — | — | — |
| Cloudlike megas | NS | 0.1 | 0.2 | 0.2 | 0.2 | 0.3 | NS | 1.0 | — | — | — | — | — | — | — | — |
| Dysplastic megas | 0.4 | 0.3 | 0.2 | 0.1 | 0.3 | 0.3 | −0.1 | 0.1 | 1.0 | — | — | — | — | — | — | — |
| Pyknotic megas | 0.2 | 0.3 | 0.3 | 0.1 | 0.2 | 0.3 | NS | 0.2 | 0.3 | 1.0 | — | — | — | — | — | — |
| Bare mega nuclei | 0.1 | 0.2 | 0.3 | NS | 0.1 | 0.3 | 0.1 | 0.2 | 0.3 | 0.6 | 1.0 | — | — | — | — | — |
| Mega size | NS | 0.3 | 0.3 | NS | 0.2 | 0.4 | 0.3 | 0.2 | NS | 0.2 | 0.2 | 1.0 | — | — | — | — |
| Cluster numbers | NS | 0.3 | 0.2 | NS | 0.2 | 0.4 | 0.2 | 0.2 | 0.1 | 0.3 | 0.2 | 0.4 | 1.0 | — | — | — |
| Cluster type | 0.2 | 0.4 | 0.1 | NS | NS | 0.3 | NS | 0.1 | 0.2 | 0.2 | 0.2 | 0.4 | 0.7 | 1.0 | — | — |
| Cluster size | 0.1 | 0.3 | 0.3 | NS | 0.2 | 0.6 | 0.2 | 0.2 | 0.2 | 0.3 | 0.2 | 0.5 | 0.7 | 0.6 | 1.0 | — |
| Paratrabec megas | 0.2 | 0.4 | 0.2 | NS | 0.1 | 0.4 | NS | 0.1 | 0.2 | 0.2 | 0.1 | 0.3 | 0.3 | 0.4 | 0.4 | 1.0 |
| New bone formation | 0.2 | 0.3 | NS | −0.1 | NS | 0.1 | NS | NS | NS | 0.2 | NS | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 |
| . | WHO diagnosis . | Reticulin grade . | Overall cellularity . | Erythroid cellularity . | Granulocyte cellularity . | Mega cellularity . | Staghorn megas . | Cloudlike megas . | Dysplastic megas . | Pyknotic megas . | Bare mega nuclei . | Mega size . | Cluster numbers . | Cluster type . | Cluster size . | Paratrabec megas . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WHO diagnosis | 1.0 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Reticulin grade | 0.7 | 1.0 | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Overall cellularity | 0.3 | 0.3 | 1.0 | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Erythroid cellularity | NS | NS | 0.3 | 1.0 | — | — | — | — | — | — | — | — | — | — | — | — |
| Granulocyte cellularity | 0.2 | 0.3 | 0.6 | 0.2 | 1.0 | — | — | — | — | — | — | — | — | — | — | — |
| Mega cellularity | 0.3 | 0.3 | 0.5 | 0.2 | 0.4 | 1.0 | — | — | — | — | — | — | — | — | — | — |
| Staghorn megas | −0.3 | NS | NS | 0.1 | NS | 0.1 | 1.0 | — | — | — | — | — | — | — | — | — |
| Cloudlike megas | NS | 0.1 | 0.2 | 0.2 | 0.2 | 0.3 | NS | 1.0 | — | — | — | — | — | — | — | — |
| Dysplastic megas | 0.4 | 0.3 | 0.2 | 0.1 | 0.3 | 0.3 | −0.1 | 0.1 | 1.0 | — | — | — | — | — | — | — |
| Pyknotic megas | 0.2 | 0.3 | 0.3 | 0.1 | 0.2 | 0.3 | NS | 0.2 | 0.3 | 1.0 | — | — | — | — | — | — |
| Bare mega nuclei | 0.1 | 0.2 | 0.3 | NS | 0.1 | 0.3 | 0.1 | 0.2 | 0.3 | 0.6 | 1.0 | — | — | — | — | — |
| Mega size | NS | 0.3 | 0.3 | NS | 0.2 | 0.4 | 0.3 | 0.2 | NS | 0.2 | 0.2 | 1.0 | — | — | — | — |
| Cluster numbers | NS | 0.3 | 0.2 | NS | 0.2 | 0.4 | 0.2 | 0.2 | 0.1 | 0.3 | 0.2 | 0.4 | 1.0 | — | — | — |
| Cluster type | 0.2 | 0.4 | 0.1 | NS | NS | 0.3 | NS | 0.1 | 0.2 | 0.2 | 0.2 | 0.4 | 0.7 | 1.0 | — | — |
| Cluster size | 0.1 | 0.3 | 0.3 | NS | 0.2 | 0.6 | 0.2 | 0.2 | 0.2 | 0.3 | 0.2 | 0.5 | 0.7 | 0.6 | 1.0 | — |
| Paratrabec megas | 0.2 | 0.4 | 0.2 | NS | 0.1 | 0.4 | NS | 0.1 | 0.2 | 0.2 | 0.1 | 0.3 | 0.3 | 0.4 | 0.4 | 1.0 |
| New bone formation | 0.2 | 0.3 | NS | −0.1 | NS | 0.1 | NS | NS | NS | 0.2 | NS | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 |
Mega indicates megakaryocyte; NS, not significant; and —, not applicable.