Table 1

Stem-cell microarray analysis of transcript regulation in Fgfr-1−/− embryoid bodies compared with Fgfr-1+/−

Gene nameSymbolFold induction
Developmental pluripotency Dppa5 9.37 
Zinc finger protein 42 Zfp42 5.70 
Protease, serine, 1 Prss1 3.19 
Pleiotrophin Ptn 3.13 
Centrosomal protein 70 Cep70 2.85 
Mesoderm-specific transcript Mest 2.71 
Developmental pluripotency associated 2 Dppa2 2.59 
Putative neuronal cell adhesion molecule Punc 2.52 
Teratocarcinoma expressed, serine rich Tera 2.46 
Nanog homeobox Nanog 2.33 
SRY-box containing gene 11 Sox11 2.30 
PDZ and LIM domain 3 Pdlim3 2.24 
Inhibitor of DNA binding 2 Id2 2.23 
Semaphorin 3A Sema3a 2.17 
SH3-binding kinase 1 Sbk1 2.15 
GATA-binding protein 3 Gata3 2.14 
Lin-7 homolog B Lin7b 2.03 
Docking protein 4 Dok4 2.02 
Gene nameSymbolFold induction
Developmental pluripotency Dppa5 9.37 
Zinc finger protein 42 Zfp42 5.70 
Protease, serine, 1 Prss1 3.19 
Pleiotrophin Ptn 3.13 
Centrosomal protein 70 Cep70 2.85 
Mesoderm-specific transcript Mest 2.71 
Developmental pluripotency associated 2 Dppa2 2.59 
Putative neuronal cell adhesion molecule Punc 2.52 
Teratocarcinoma expressed, serine rich Tera 2.46 
Nanog homeobox Nanog 2.33 
SRY-box containing gene 11 Sox11 2.30 
PDZ and LIM domain 3 Pdlim3 2.24 
Inhibitor of DNA binding 2 Id2 2.23 
Semaphorin 3A Sema3a 2.17 
SH3-binding kinase 1 Sbk1 2.15 
GATA-binding protein 3 Gata3 2.14 
Lin-7 homolog B Lin7b 2.03 
Docking protein 4 Dok4 2.02 

All P values were less than .001.

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