Table 1

Frequency of progeny from double heterozygous HCII+/−apoE+/− breeding pairs

apoE+/+apoE+/−apoE−/−Total
HCII+/+ 56 (34) 52 (67) 18 (34) 126 (134) 
HCII+/− 111 (67) 94 (134) 43 (67) 248 (269) 
HCII−/− 69 (34) 66 (67) 28 (34) 163 (134) 
Total 236 (134) 212 (269) 89 (134) 537 
apoE+/+apoE+/−apoE−/−Total
HCII+/+ 56 (34) 52 (67) 18 (34) 126 (134) 
HCII+/− 111 (67) 94 (134) 43 (67) 248 (269) 
HCII−/− 69 (34) 66 (67) 28 (34) 163 (134) 
Total 236 (134) 212 (269) 89 (134) 537 

Genotypes were determined for surviving pups at 3 weeks of age. Data are number of progeny with the expected Mendelian frequencies of each genotype (rounded to the nearest whole number) in parentheses.