Table 1.

Prevalence of clinically apparent septic transfusion reactions, before (A) and after (B) implementation of AABB standard 5.1.5.1.

Septic ReactionsFatal Septic Reactions
StudyPooled RDPsSDPsPooled RDPsSDPs
Abbreviations: RDPs, random donor platelets; SDPs, single donor (apheresis) platelets. 
A. Pre-standard 5.1.5.1. 
 Ness et al (Hopkins)12  1/2,500 1/13,000 1/16,000 1/67,000 
 Perez et al (BACTHEM)13  1/14,000 1/31,000 1/140,000 
 Kuehnert et al (BaCon)14  1/100,000 1/100,000 1/500,000 1/450,000 
B. Post-standard 5.1.5.1 
 Fang et al15  ND 1/117,000 ND 1/350,000 
Septic ReactionsFatal Septic Reactions
StudyPooled RDPsSDPsPooled RDPsSDPs
Abbreviations: RDPs, random donor platelets; SDPs, single donor (apheresis) platelets. 
A. Pre-standard 5.1.5.1. 
 Ness et al (Hopkins)12  1/2,500 1/13,000 1/16,000 1/67,000 
 Perez et al (BACTHEM)13  1/14,000 1/31,000 1/140,000 
 Kuehnert et al (BaCon)14  1/100,000 1/100,000 1/500,000 1/450,000 
B. Post-standard 5.1.5.1 
 Fang et al15  ND 1/117,000 ND 1/350,000 

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