Table 1.

Markers of poor outcome for factor VIII immune tolerance induction (ITI).

  • Pre-ITI inhibitor titer > 10 Bethesda units (BUs)

  • Peak historic inhibitor titer > 200 BUs

  • Presence of inhibitor > 2 years

 
  • Pre-ITI inhibitor titer > 10 Bethesda units (BUs)

  • Peak historic inhibitor titer > 200 BUs

  • Presence of inhibitor > 2 years