Table 3. Patient details and tumor... | American Society of Hematology

Table 3.

Patient details and tumor response on day 36

Patient ID	Termination/reason	CG/molecular	Disease stage	Prognosis/classification	Baseline QTc	Day 1 PB blast count, × 10⁹/L	Day 36 PB blast count, × 10⁹/L	Day 1 BM blast, %	Day 36 BM blast, %
1	Normal	46,XY,del(7)(q11.2)	Refractory	High/refractory score	436.6	11.6	14.6	54	69
2	Normal	46,XY/normal	Relapse	Intermediate/EPI score	407	0	0.4	46	7
3	Early/DLT	46,XX,t(8;14)(p11.2;q32.1)	Relapse-2	Intermediate/refractory score	445	15.1	NE	89	NE
4	Early/disease progression	46,XY, del(9)(q13q22)/FLT3-ITD+	AML-MRC diagnosis	Intermediate/ ELN	409.3	24.8	135.3	87	78*
5	Normal	46,XX/normal	Relapse	High/EPI score	419	1	1.8	61	70
6	Normal	46,XY/FLT3-ITD⁺	AML-MRC diagnosis	Intermediate/ELN	438	2.9	8.3	25	80
7	Normal	46,XX, del(5)(q13q33)/FLT3-D835+	Relapse	High/ EPI score	407.3	109.7	37.1	94	71*
8	Early/patient request	46,XX, t(4;6)(q23;p25), del(7)(q22q34), del(20)(q11.2q13.1)	Relapse	Intermediate/EPI score	411	5.4	NE	81	NE
9	Normal	46,XY/normal	AML-MRC diagnosis	Intermediate/ELN	455	0	0	45	34
10	Normal	46,XY/normal	Relapse	High/EPI score	419	2.5	1.2	64	74
11	Normal	46,XY, der(22) t(1;22)(q11;p11.2)	Relapse	Intermediate/EPI score	424	12	16.6	73	69†
12	Early/DLT	Complex karyotype	AML-MRC diagnosis	Poor/ELN	432	0	NE	22	NE
13	Early/DLT	46,XY/normal	Relapse	Intermediate/EPI score	NA	0.2	NE	56	NE

Patient ID	Termination/reason	CG/molecular	Disease stage	Prognosis/classification	Baseline QTc	Day 1 PB blast count, × 10⁹/L	Day 36 PB blast count, × 10⁹/L	Day 1 BM blast, %	Day 36 BM blast, %
1	Normal	46,XY,del(7)(q11.2)	Refractory	High/refractory score	436.6	11.6	14.6	54	69
2	Normal	46,XY/normal	Relapse	Intermediate/EPI score	407	0	0.4	46	7
3	Early/DLT	46,XX,t(8;14)(p11.2;q32.1)	Relapse-2	Intermediate/refractory score	445	15.1	NE	89	NE
4	Early/disease progression	46,XY, del(9)(q13q22)/FLT3-ITD+	AML-MRC diagnosis	Intermediate/ ELN	409.3	24.8	135.3	87	78*
5	Normal	46,XX/normal	Relapse	High/EPI score	419	1	1.8	61	70
6	Normal	46,XY/FLT3-ITD⁺	AML-MRC diagnosis	Intermediate/ELN	438	2.9	8.3	25	80
7	Normal	46,XX, del(5)(q13q33)/FLT3-D835+	Relapse	High/ EPI score	407.3	109.7	37.1	94	71*
8	Early/patient request	46,XX, t(4;6)(q23;p25), del(7)(q22q34), del(20)(q11.2q13.1)	Relapse	Intermediate/EPI score	411	5.4	NE	81	NE
9	Normal	46,XY/normal	AML-MRC diagnosis	Intermediate/ELN	455	0	0	45	34
10	Normal	46,XY/normal	Relapse	High/EPI score	419	2.5	1.2	64	74
11	Normal	46,XY, der(22) t(1;22)(q11;p11.2)	Relapse	Intermediate/EPI score	424	12	16.6	73	69†
12	Early/DLT	Complex karyotype	AML-MRC diagnosis	Poor/ELN	432	0	NE	22	NE
13	Early/DLT	46,XY/normal	Relapse	Intermediate/EPI score	NA	0.2	NE	56	NE

ELN, European LeukemiaNet; EPI, European Prognostic Index; ID, identification; NE, nonevaluable.

Day 22 values indicated because day 36 value was unavailable.

Value reported in a follow-up later than day 36.