Table 8. NNH and NNT in ASPIRE and... | American Society of Hematology

Table 8.

NNH and NNT in ASPIRE and ENDEAVOR trials

	ASPIRE	ENDEAVOR
Unfavorable effects: NNH (subject year)
Grade ≥3 cardiac failure*	102.8	30.8
Grade ≥3 hypertension†	75.1	12.9
Favorable effect: NNT (subject year)
PFS	8.2	2.5

	ASPIRE	ENDEAVOR
Unfavorable effects: NNH (subject year)
Grade ≥3 cardiac failure*	102.8	30.8
Grade ≥3 hypertension†	75.1	12.9
Favorable effect: NNT (subject year)
PFS	8.2	2.5

Based on standardized MedDRA query, narrow scope.

Based on preferred term.