Table 4.

Proportion of cases and controls with novel surface HLA-DRB1tFVIII peptide binding combinations by mutation

Controls with >10 novel surface HLA-DRB1–tFVIII peptide binding combinationsCases with >10 novel surface HLA-DRB1–tFVIII peptide binding combinations
High-risk mutation 5 (62.5) 11 (78.6) 
Other 6 (20.7) 2 (33.3) 
Controls with >10 novel surface HLA-DRB1–tFVIII peptide binding combinationsCases with >10 novel surface HLA-DRB1–tFVIII peptide binding combinations
High-risk mutation 5 (62.5) 11 (78.6) 
Other 6 (20.7) 2 (33.3) 

Data are n (%). High-risk mutation is p.Arg162Cys, p.Asn1941Ser, p.Arg2169His, p.Trp2248Cys.

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