Univariate and multivariate analysis of variables affecting OS
| Variable . | Univariate analysis . | Multivariate analysis . | ||||
|---|---|---|---|---|---|---|
| HR . | 95% CI . | P . | HR . | 95% CI . | P . | |
| Age, ≥70 y | 2.78 | 1.51-5.14 | .001 | 2.20 | 1.06-4.60 | .02 |
| Male sex | 1.16 | 0.69-1.96 | .571 | — | — | — |
| Creatinine level >2.0 mg/dL | 2.84 | 1.61-5.04 | <.001 | 2.42 | 1.31-4.46 | .004 |
| D-S stage 3 | 3.05 | 1.44-6.44 | .004 | 1.99 | 0.83-4.77 | .12 |
| R-ISS stage 3 | 1.63 | 0.95-2.80 | .08 | 0.92 | 0.50-1.68 | .78 |
| % of BM CD138+ cells | 1.01 | 1.00-1.02 | .286 | — | — | — |
| HDT + ASCT | 0.44 | 0.22-0.88 | .019 | 0.66 | 0.29-1.51 | .32 |
| MDCT pattern | ||||||
| Fatty | 1 (reference) | 1 (reference) | ||||
| Focal/scattered | 3.08 | 1.53-6.21 | .002 | 2.51 | 1.14-5.56 | .023 |
| Diffuse | 4.94 | 2.34-10.42 | <.001 | 4.12 | 1.74-9.77 | .001 |
| Variable . | Univariate analysis . | Multivariate analysis . | ||||
|---|---|---|---|---|---|---|
| HR . | 95% CI . | P . | HR . | 95% CI . | P . | |
| Age, ≥70 y | 2.78 | 1.51-5.14 | .001 | 2.20 | 1.06-4.60 | .02 |
| Male sex | 1.16 | 0.69-1.96 | .571 | — | — | — |
| Creatinine level >2.0 mg/dL | 2.84 | 1.61-5.04 | <.001 | 2.42 | 1.31-4.46 | .004 |
| D-S stage 3 | 3.05 | 1.44-6.44 | .004 | 1.99 | 0.83-4.77 | .12 |
| R-ISS stage 3 | 1.63 | 0.95-2.80 | .08 | 0.92 | 0.50-1.68 | .78 |
| % of BM CD138+ cells | 1.01 | 1.00-1.02 | .286 | — | — | — |
| HDT + ASCT | 0.44 | 0.22-0.88 | .019 | 0.66 | 0.29-1.51 | .32 |
| MDCT pattern | ||||||
| Fatty | 1 (reference) | 1 (reference) | ||||
| Focal/scattered | 3.08 | 1.53-6.21 | .002 | 2.51 | 1.14-5.56 | .023 |
| Diffuse | 4.94 | 2.34-10.42 | <.001 | 4.12 | 1.74-9.77 | .001 |
Abbreviations are explained in Tables 1 and 2.