Cox regression analysis regarding the impact of CR criteria not met on OS and RFS
| . | Non-sCR vs sCR . | |||
|---|---|---|---|---|
| OS . | RFS . | |||
| HR . | 95% CI . | HR . | 95% CI . | |
| Incomplete platelet recovery | ||||
| Crude | 1.81 | 1.49-2.20 | 1.68 | 1.39-2.04 |
| Age and sex adjusted | 1.61 | 1.32-1.97 | 1.56 | 1.28-1.89 |
| Fully adjusted* | 1.61 | 1.39-2.00 | 1.56 | 1.26-1.93 |
| Fully adjusted including remaining CR criteria† | 1.27 | 0.97-1.66 | 1.26 | 0.97-1.64 |
| Incomplete neutrophil recovery | ||||
| Crude | 1.33 | 1.05-1.69 | 1.27 | 1.01-1.61 |
| Age and sex adjusted | 1.37 | 1.08-1.75 | 1.29 | 1.02-1.63 |
| Fully adjusted* | 1.48 | 1.14-1.92 | 1.39 | 1.08-1.79 |
| Fully adjusted including remaining CR criteria† | 1.38 | 1.05-1.79 | 1.31 | 1.01-1.69 |
| No independence of red cell transfusion | ||||
| Crude | 1.50 | 1.19-1.89 | 1.33 | 1.06-1.67 |
| Age and sex adjusted | 1.41 | 1.11-1.78 | 1.28 | 1.01-1.61 |
| Fully adjusted* | 1.40 | 1.08-1.82 | 1.27 | 0.98-1.64 |
| Fully adjusted including remaining CR criteria† | 1.44 | 1.06-1.95 | 1.32 | 0.97-1.78 |
| . | Non-sCR vs sCR . | |||
|---|---|---|---|---|
| OS . | RFS . | |||
| HR . | 95% CI . | HR . | 95% CI . | |
| Incomplete platelet recovery | ||||
| Crude | 1.81 | 1.49-2.20 | 1.68 | 1.39-2.04 |
| Age and sex adjusted | 1.61 | 1.32-1.97 | 1.56 | 1.28-1.89 |
| Fully adjusted* | 1.61 | 1.39-2.00 | 1.56 | 1.26-1.93 |
| Fully adjusted including remaining CR criteria† | 1.27 | 0.97-1.66 | 1.26 | 0.97-1.64 |
| Incomplete neutrophil recovery | ||||
| Crude | 1.33 | 1.05-1.69 | 1.27 | 1.01-1.61 |
| Age and sex adjusted | 1.37 | 1.08-1.75 | 1.29 | 1.02-1.63 |
| Fully adjusted* | 1.48 | 1.14-1.92 | 1.39 | 1.08-1.79 |
| Fully adjusted including remaining CR criteria† | 1.38 | 1.05-1.79 | 1.31 | 1.01-1.69 |
| No independence of red cell transfusion | ||||
| Crude | 1.50 | 1.19-1.89 | 1.33 | 1.06-1.67 |
| Age and sex adjusted | 1.41 | 1.11-1.78 | 1.28 | 1.01-1.61 |
| Fully adjusted* | 1.40 | 1.08-1.82 | 1.27 | 0.98-1.64 |
| Fully adjusted including remaining CR criteria† | 1.44 | 1.06-1.95 | 1.32 | 0.97-1.78 |
Adjusted for age, sex, World Health Organization performance score at diagnosis, leukocyte count at diagnosis, CR as response after first or second induction therapy, and cytogenetic risk group.
Adjusted for the abovementioned variables as well as the remaining sCR criteria (ie, incomplete platelet recovery, incomplete neutrophil recovery, and no independence of red cell transfusion).