Relationship between patients and the biological characteristics and (a) presence of silent WMCs and (b) WMC burden (univariable analysis)
| . | Silent WMCs . | . | . | |
|---|---|---|---|---|
| . | Yes (n = 41) . | No (n = 42) . | (a) P . | (b) P . |
| Age, y | 45.71 (11.26) | 40.96 (7.44) | .03 | .02 |
| Headache, n (%) | 6 (15) | 7 (17) | .80 | .61 |
| Hypertension, n (%) | 9 (22) | 1 (2) | .02 | .02 |
| Smoking, n (%) | 3 (7) | 2 (5) | .63 | .83 |
| White blood cell count, ×109/L | 10.19 (2.23) | 10.60 (1.97) | .38 | .39 |
| Red blood cell count, ×109/L | 2.84 (0.62) | 2.69 (0.51) | .23 | .32 |
| Hemoglobin, g/L | 8.34 (1.16) | 8.66 (1.26) | .23 | .41 |
| Hematocrit, % | 24.29 (3.80) | 25.00 (4.06) | .43 | .69 |
| Mean corpuscular volume, fL | 87.29 (9.15) | 93.70 (9.16) | <.01 | .03 |
| Mean corpuscular hemoglobin concentration, g/dL | 29.71 (3.44) | 31.96 (3.46) | <.01 | .03 |
| Reticulocyte count, ×109/L | 284.31 (84.37) | 282.66 (97.53) | .93 | 1.00 |
| Platelet count, ×109/L | 347.13 (99.71) | 385.50 (97.82) | .09 | .34 |
| Lactate dehydrogenase, U/L | 461.83 (193.96) | 398.50 (165.01) | .13 | .33 |
| Bilirubin, µmol/L | 61.24 (30.25) | 60.95 (28.15) | .97 | .84 |
| %HbF | 5.57 (4.14) | 9.46 (5.93) | <.01 | <.01 |
| . | Silent WMCs . | . | . | |
|---|---|---|---|---|
| . | Yes (n = 41) . | No (n = 42) . | (a) P . | (b) P . |
| Age, y | 45.71 (11.26) | 40.96 (7.44) | .03 | .02 |
| Headache, n (%) | 6 (15) | 7 (17) | .80 | .61 |
| Hypertension, n (%) | 9 (22) | 1 (2) | .02 | .02 |
| Smoking, n (%) | 3 (7) | 2 (5) | .63 | .83 |
| White blood cell count, ×109/L | 10.19 (2.23) | 10.60 (1.97) | .38 | .39 |
| Red blood cell count, ×109/L | 2.84 (0.62) | 2.69 (0.51) | .23 | .32 |
| Hemoglobin, g/L | 8.34 (1.16) | 8.66 (1.26) | .23 | .41 |
| Hematocrit, % | 24.29 (3.80) | 25.00 (4.06) | .43 | .69 |
| Mean corpuscular volume, fL | 87.29 (9.15) | 93.70 (9.16) | <.01 | .03 |
| Mean corpuscular hemoglobin concentration, g/dL | 29.71 (3.44) | 31.96 (3.46) | <.01 | .03 |
| Reticulocyte count, ×109/L | 284.31 (84.37) | 282.66 (97.53) | .93 | 1.00 |
| Platelet count, ×109/L | 347.13 (99.71) | 385.50 (97.82) | .09 | .34 |
| Lactate dehydrogenase, U/L | 461.83 (193.96) | 398.50 (165.01) | .13 | .33 |
| Bilirubin, µmol/L | 61.24 (30.25) | 60.95 (28.15) | .97 | .84 |
| %HbF | 5.57 (4.14) | 9.46 (5.93) | <.01 | <.01 |
Values are mean (± SD), unless otherwise indicated.