Results from multivariable Cox regression analysis in patients treated with PAD
| . | All patients . | High-risk patients . | ||||||
|---|---|---|---|---|---|---|---|---|
| . | PFS . | OS . | PFS . | OS . | ||||
| . | HR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | P . |
| Subclone | 1.28 (0.85-1.92) | .233 | 2.07 (1.15-3.73) | .016 | 2.11 (1.01-4.43) | .048 | 3.24 (1.19-8.83) | .022 |
| ISS II | 1.20 (0.77-1.88) | .414 | 1.85 (1.01-3.38) | .046 | 0.60 (0.26-1.37) | .227 | 0.93 (0.34-2.55) | .890 |
| ISS III | 1.41 (0.86-2.32) | .176 | 1.63 (0.82-3.26) | .167 | 0.78 (0.29-2.09) | .625 | 0.76 (0.23-2.53) | .654 |
| Age | 1.01 (0.98-1.03) | .653 | 1.04 (1.00-1.08) | .034 | 0.99 (0.94-1.03) | .553 | 1.00 (0.94-1.06) | .963 |
| High LDH | 2.28 (1.38-3.76) | .001 | 3.29 (1.79-6.06) | .0001 | 2.19 (0.73-6.55) | .160 | 4.68 (1.52-14.4) | .007 |
| HR main | 1.61 (1.06-2.46) | .025 | 2.06 (1.23-3.46) | .006 | — | — | — | — |
| . | All patients . | High-risk patients . | ||||||
|---|---|---|---|---|---|---|---|---|
| . | PFS . | OS . | PFS . | OS . | ||||
| . | HR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | P . |
| Subclone | 1.28 (0.85-1.92) | .233 | 2.07 (1.15-3.73) | .016 | 2.11 (1.01-4.43) | .048 | 3.24 (1.19-8.83) | .022 |
| ISS II | 1.20 (0.77-1.88) | .414 | 1.85 (1.01-3.38) | .046 | 0.60 (0.26-1.37) | .227 | 0.93 (0.34-2.55) | .890 |
| ISS III | 1.41 (0.86-2.32) | .176 | 1.63 (0.82-3.26) | .167 | 0.78 (0.29-2.09) | .625 | 0.76 (0.23-2.53) | .654 |
| Age | 1.01 (0.98-1.03) | .653 | 1.04 (1.00-1.08) | .034 | 0.99 (0.94-1.03) | .553 | 1.00 (0.94-1.06) | .963 |
| High LDH | 2.28 (1.38-3.76) | .001 | 3.29 (1.79-6.06) | .0001 | 2.19 (0.73-6.55) | .160 | 4.68 (1.52-14.4) | .007 |
| HR main | 1.61 (1.06-2.46) | .025 | 2.06 (1.23-3.46) | .006 | — | — | — | — |
Bold type indicates significant P values.