Table 4.

The 16 most unevenly distributed variants between continental groups as measured by SD of allele frequency

GeneIDGenomic changeCDS changeCount (n)AFRAMREASEURSASSD
ACKR1 rs2814778 NG_011626.1:g.5174T>C c.−67T>C 1334 0.96 0.08 0 0.01 0 0.42 
ACKR1 rs55872368 NG_011626.1:g.7347G>T  1488 0.87 0.17 0 0.16 0.06 0.35 
A4GALT rs6002915 NG_007495.1:g.19787C>T  1340 0.81 0.13 0.01 0.11 0.06 0.33 
ACKR1 rs12075 NG_011626.1:g.5845G>A c.125G>A 2707 0.98 0.54 0.08 0.60 0.36 0.33 
RHD rs28568805 NG_007494.1:g.1418C>A  3956 0.26 0.91 1.00 0.99 1.00 0.32 
CR1 rs17047661 NG_007481.1:g.118417A>G c.4801A>G 984 0.71 0.05 0 0.01 0 0.31 
ACKR1 rs863004 NG_011626.1:g.7322C>T  2106 0.88 0.31 0.05 0.42 0.26 0.31 
ABCG2 rs11373616 NG_032067.2:g.133727_133728insT  3531 0.21 0.85 0.96 0.87 0.84 0.30 
ABCG2 rs2725265 NG_032067.2:g.131659C>T  3179 0.14 0.70 0.78 0.91 0.81 0.30 
ABCG2 rs2725264 NG_032067.2:g.131366G>A  3180 0.15 0.70 0.78 0.91 0.81 0.30 
RHD rs599792 NG_007494.1:g.29275A>C  3042 0.12 0.65 0.80 0.75 0.88 0.30 
ABCG2 rs146880547 NG_032067.2:g.131659_131660insT  3051 0.13 0.69 0.73 0.89 0.79 0.30 
AQP1 rs1465216 NG_007475.2:g.47740T>C  2168 0.86 0.13 0.35 0.13 0.47 0.30 
RHD rs3927483 NG_007494.1:g.63145C>A  3056 0.13 0.65 0.79 0.76 0.88 0.30 
AQP1 rs7782345 NG_007475.2:g.22880T>G  2130 0.86 0.13 0.38 0.12 0.41 0.30 
ABCG2 rs5860115 NG_032067.2:g.127963_127964insT  3099 0.14 0.69 0.78 0.90 0.76 0.30 
GeneIDGenomic changeCDS changeCount (n)AFRAMREASEURSASSD
ACKR1 rs2814778 NG_011626.1:g.5174T>C c.−67T>C 1334 0.96 0.08 0 0.01 0 0.42 
ACKR1 rs55872368 NG_011626.1:g.7347G>T  1488 0.87 0.17 0 0.16 0.06 0.35 
A4GALT rs6002915 NG_007495.1:g.19787C>T  1340 0.81 0.13 0.01 0.11 0.06 0.33 
ACKR1 rs12075 NG_011626.1:g.5845G>A c.125G>A 2707 0.98 0.54 0.08 0.60 0.36 0.33 
RHD rs28568805 NG_007494.1:g.1418C>A  3956 0.26 0.91 1.00 0.99 1.00 0.32 
CR1 rs17047661 NG_007481.1:g.118417A>G c.4801A>G 984 0.71 0.05 0 0.01 0 0.31 
ACKR1 rs863004 NG_011626.1:g.7322C>T  2106 0.88 0.31 0.05 0.42 0.26 0.31 
ABCG2 rs11373616 NG_032067.2:g.133727_133728insT  3531 0.21 0.85 0.96 0.87 0.84 0.30 
ABCG2 rs2725265 NG_032067.2:g.131659C>T  3179 0.14 0.70 0.78 0.91 0.81 0.30 
ABCG2 rs2725264 NG_032067.2:g.131366G>A  3180 0.15 0.70 0.78 0.91 0.81 0.30 
RHD rs599792 NG_007494.1:g.29275A>C  3042 0.12 0.65 0.80 0.75 0.88 0.30 
ABCG2 rs146880547 NG_032067.2:g.131659_131660insT  3051 0.13 0.69 0.73 0.89 0.79 0.30 
AQP1 rs1465216 NG_007475.2:g.47740T>C  2168 0.86 0.13 0.35 0.13 0.47 0.30 
RHD rs3927483 NG_007494.1:g.63145C>A  3056 0.13 0.65 0.79 0.76 0.88 0.30 
AQP1 rs7782345 NG_007475.2:g.22880T>G  2130 0.86 0.13 0.38 0.12 0.41 0.30 
ABCG2 rs5860115 NG_032067.2:g.127963_127964insT  3099 0.14 0.69 0.78 0.90 0.76 0.30 

AFR, African; AMR, admixed American; EAS, East Asian; EUR, European; SAS, South Asian.

View Large
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal