Degree of variation in blood group genes measured as number of variants per kilobase
| System . | Gene . | Total* . | CDS . | Exon . | Intron . |
|---|---|---|---|---|---|
| ABO | ABO | 35.9 | 63.8 | 53.2 | 36.3 |
| MNS | GYPA | 35.0 | 41.9 | 28.7 | 35.1 |
| GYPB | 42.7 | 68.8 | 58.8 | 41.8 | |
| P1PK | A4GALT | 35.1 | 33.9 | 39.7 | 35.4 |
| RH | RHD | 28.0 | 48.6 | 39.1 | 27.3 |
| RHCE | 26.5 | 39.9 | 35.2 | 26.3 | |
| LU | BCAM | 36.6 | 58.8 | 55.4 | 33.7 |
| KEL | KEL | 31.2 | 40.5 | 38.5 | 29.2 |
| LE | FUT3 | 40.0 | 68.1 | 47.1 | 32.5 |
| FY | ACKR1 | 30.7 | 21.8 | 30.9 | 33.3 |
| JK | SLC14A1 | 32.3 | 35.0 | 27.4 | 32.6 |
| DI | SLC4A1 | 29.8 | 37.6 | 32.7 | 29.4 |
| YT | ACHE | 29.5 | 24.8 | 24.3 | 30.0 |
| XG | XG | 31.8 | 31.3 | 18.4 | 32.7 |
| CD99 | 38.2 | 52.0 | 56.6 | 38.5 | |
| SC | ERMAP | 26.9 | 39.9 | 31.0 | 25.0 |
| DO | ART4 | 25.7 | 39.2 | 35.0 | 26.4 |
| CO | AQP1 | 33.4 | 43.2 | 31.4 | 33.5 |
| LW | ICAM4 | 30.1 | 22.1 | 20.1 | 36.2 |
| CH/RG | C4A | 6.5 | 5.5 | 5.3 | 1.8 |
| C4B | 4.9 | 4.4 | 4.2 | 1.5 | |
| H | FUT1 | 33.9 | 37.3 | 28.7 | 30.3 |
| FUT2 | 37.6 | 78.5 | 52.3 | 30.4 | |
| XK | XK | 18.9 | 8.2 | 17.7 | 19.9 |
| GE | GYPC | 36.0 | 62.0 | 40.8 | 36.7 |
| CROM | CD55 | 25.2 | 26.2 | 24.7 | 25.5 |
| KN | CR1 | 20.9 | 27.9 | 27.6 | 20.1 |
| IN | CD44 | 31.1 | 23.9 | 29.0 | 31.2 |
| OK | BSG | 49.9 | 49.4 | 54.0 | 51.5 |
| RAPH | CD151 | 45.6 | 31.5 | 41.3 | 52.4 |
| JMH | SEMA7A | 29.6 | 27.0 | 27.8 | 29.8 |
| I | GCNT2 | 38.1 | 31.4 | 33.3 | 32.1 |
| GLOB | B3GALNT1 | 26.9 | 9.0 | 22.5 | 27.6 |
| GIL | AQP3 | 32.5 | 15.9 | 31.0 | 30.4 |
| RHAG | RHAG | 31.0 | 30.1 | 25.9 | 31.2 |
| FORS | GBGT1 | 35.1 | 62.3 | 48.9 | 32.2 |
| JR | ABCG2 | 28.9 | 35.6 | 32.5 | 30.4 |
| LAN | ABCB6 | 30.8 | 31.6 | 34.1 | 29.3 |
| VEL | SMIM1 | 35.6 | 12.7 | 29.3 | 34.0 |
| CD59 | CD59 | 28.3 | 46.5 | 32.0 | 27.9 |
| AUG | SLC29A1 | 28.2 | 22.0 | 24.3 | 32.5 |
| Associated genes | GATA1 | 20.2 | 20.9 | 22.3 | 20.8 |
| KLF1 | 28.4 | 27.5 | 31.0 | 24.0 |
| System . | Gene . | Total* . | CDS . | Exon . | Intron . |
|---|---|---|---|---|---|
| ABO | ABO | 35.9 | 63.8 | 53.2 | 36.3 |
| MNS | GYPA | 35.0 | 41.9 | 28.7 | 35.1 |
| GYPB | 42.7 | 68.8 | 58.8 | 41.8 | |
| P1PK | A4GALT | 35.1 | 33.9 | 39.7 | 35.4 |
| RH | RHD | 28.0 | 48.6 | 39.1 | 27.3 |
| RHCE | 26.5 | 39.9 | 35.2 | 26.3 | |
| LU | BCAM | 36.6 | 58.8 | 55.4 | 33.7 |
| KEL | KEL | 31.2 | 40.5 | 38.5 | 29.2 |
| LE | FUT3 | 40.0 | 68.1 | 47.1 | 32.5 |
| FY | ACKR1 | 30.7 | 21.8 | 30.9 | 33.3 |
| JK | SLC14A1 | 32.3 | 35.0 | 27.4 | 32.6 |
| DI | SLC4A1 | 29.8 | 37.6 | 32.7 | 29.4 |
| YT | ACHE | 29.5 | 24.8 | 24.3 | 30.0 |
| XG | XG | 31.8 | 31.3 | 18.4 | 32.7 |
| CD99 | 38.2 | 52.0 | 56.6 | 38.5 | |
| SC | ERMAP | 26.9 | 39.9 | 31.0 | 25.0 |
| DO | ART4 | 25.7 | 39.2 | 35.0 | 26.4 |
| CO | AQP1 | 33.4 | 43.2 | 31.4 | 33.5 |
| LW | ICAM4 | 30.1 | 22.1 | 20.1 | 36.2 |
| CH/RG | C4A | 6.5 | 5.5 | 5.3 | 1.8 |
| C4B | 4.9 | 4.4 | 4.2 | 1.5 | |
| H | FUT1 | 33.9 | 37.3 | 28.7 | 30.3 |
| FUT2 | 37.6 | 78.5 | 52.3 | 30.4 | |
| XK | XK | 18.9 | 8.2 | 17.7 | 19.9 |
| GE | GYPC | 36.0 | 62.0 | 40.8 | 36.7 |
| CROM | CD55 | 25.2 | 26.2 | 24.7 | 25.5 |
| KN | CR1 | 20.9 | 27.9 | 27.6 | 20.1 |
| IN | CD44 | 31.1 | 23.9 | 29.0 | 31.2 |
| OK | BSG | 49.9 | 49.4 | 54.0 | 51.5 |
| RAPH | CD151 | 45.6 | 31.5 | 41.3 | 52.4 |
| JMH | SEMA7A | 29.6 | 27.0 | 27.8 | 29.8 |
| I | GCNT2 | 38.1 | 31.4 | 33.3 | 32.1 |
| GLOB | B3GALNT1 | 26.9 | 9.0 | 22.5 | 27.6 |
| GIL | AQP3 | 32.5 | 15.9 | 31.0 | 30.4 |
| RHAG | RHAG | 31.0 | 30.1 | 25.9 | 31.2 |
| FORS | GBGT1 | 35.1 | 62.3 | 48.9 | 32.2 |
| JR | ABCG2 | 28.9 | 35.6 | 32.5 | 30.4 |
| LAN | ABCB6 | 30.8 | 31.6 | 34.1 | 29.3 |
| VEL | SMIM1 | 35.6 | 12.7 | 29.3 | 34.0 |
| CD59 | CD59 | 28.3 | 46.5 | 32.0 | 27.9 |
| AUG | SLC29A1 | 28.2 | 22.0 | 24.3 | 32.5 |
| Associated genes | GATA1 | 20.2 | 20.9 | 22.3 | 20.8 |
| KLF1 | 28.4 | 27.5 | 31.0 | 24.0 |
Total includes exons, introns, and 5′ and 3′ flanking regions.