Multivariable Cox proportional hazard regression model for ONFH among SCD patients, California, 1991-2013
| . | All SCD patients . | Subanalysis of October 2003-2013 . | ||||
|---|---|---|---|---|---|---|
| Variable . | HR . | 95% CI . | P . | HR . | 95% CI . | P . |
| Sex | ||||||
| Male | 1.09 | 0.97-1.23 | .1366 | 1.06 | 0.92-1.23 | .4157 |
| Female | REF | — | — | REF | — | — |
| SCD severity | ||||||
| Severe | 2.52 | 2.23-2.84 | <.0001 | 2.77 | 2.38-3.23 | <.0001 |
| Less severe | REF | — | — | REF | — | — |
| Acute chest syndrome* | ||||||
| Yes | NA | 1.61 | 1.35-1.91 | <.0001 | ||
| No | NA | REF | — | — | ||
| . | All SCD patients . | Subanalysis of October 2003-2013 . | ||||
|---|---|---|---|---|---|---|
| Variable . | HR . | 95% CI . | P . | HR . | 95% CI . | P . |
| Sex | ||||||
| Male | 1.09 | 0.97-1.23 | .1366 | 1.06 | 0.92-1.23 | .4157 |
| Female | REF | — | — | REF | — | — |
| SCD severity | ||||||
| Severe | 2.52 | 2.23-2.84 | <.0001 | 2.77 | 2.38-3.23 | <.0001 |
| Less severe | REF | — | — | REF | — | — |
| Acute chest syndrome* | ||||||
| Yes | NA | 1.61 | 1.35-1.91 | <.0001 | ||
| No | NA | REF | — | — | ||
Adjusted for race/ethnicity and stratified by birth cohort.
REF, reference.
Acute chest syndrome was included as a time-dependent variable.