Other clinical manifestations at initial diagnosis of chronic graft-versus-host disease (GVHD) and ever noted, based on 324 patients diagnosed with chronic GVHD according to NIH consensus criteria, transplanted at FHCRC 2003–2005.(M. Flowers, unpublished data)
. | At onset, % . | Ever, % . |
---|---|---|
Sites involved | ||
Skin | 74 | 81 |
Finger/toenail/mouth | 8 | 19 |
Mouth | 87 | 89 |
Eyes | 34 | 47 |
G.I. tract | 40 | 48 |
Esophagus | 1 | 5 |
Liver | 35 | 47 |
Vagina/penis | 4 | 10 |
Lungs | 3 | 14 |
Joints | 7 | 15 |
Muscle | 2 | 2 |
Serosa | 2 | 2 |
Myofascial | 6 | 16 |
Clinical manifestations/complications | ||
Weight loss | 22 | 31 |
Joint contracture | 2 | 7 |
Malabsorption | <1 | 1 |
Keratoconjunctivitis | 3 | 8 |
Cutaneous sclerosis | 4 | 13 |
Esophageal stricture | <1 | 1 |
Bronchiolitis obliterans syndrome | <1 | 7 |
Eosinophilia | 14 | 20 |
Bronchiolitis obliterans organizing pneumonia | 2 | 4 |
Other characteristics | ||
Progressive onset | 13 | |
Quiescent onset | 60 | |
De novo onset | 27 | |
On steroids at diagnosis | 34 | |
Platelets < 100,000 at diagnosis | 31 |
. | At onset, % . | Ever, % . |
---|---|---|
Sites involved | ||
Skin | 74 | 81 |
Finger/toenail/mouth | 8 | 19 |
Mouth | 87 | 89 |
Eyes | 34 | 47 |
G.I. tract | 40 | 48 |
Esophagus | 1 | 5 |
Liver | 35 | 47 |
Vagina/penis | 4 | 10 |
Lungs | 3 | 14 |
Joints | 7 | 15 |
Muscle | 2 | 2 |
Serosa | 2 | 2 |
Myofascial | 6 | 16 |
Clinical manifestations/complications | ||
Weight loss | 22 | 31 |
Joint contracture | 2 | 7 |
Malabsorption | <1 | 1 |
Keratoconjunctivitis | 3 | 8 |
Cutaneous sclerosis | 4 | 13 |
Esophageal stricture | <1 | 1 |
Bronchiolitis obliterans syndrome | <1 | 7 |
Eosinophilia | 14 | 20 |
Bronchiolitis obliterans organizing pneumonia | 2 | 4 |
Other characteristics | ||
Progressive onset | 13 | |
Quiescent onset | 60 | |
De novo onset | 27 | |
On steroids at diagnosis | 34 | |
Platelets < 100,000 at diagnosis | 31 |