Table 1.

Recommended evaluation for patients with newly diagnosed MALT lymphoma.

All patients Diagnostic biopsy (fine needle aspiration 
 [FNA] is not sufficient) 
 Complete history and physical examination 
 Laboratory evaluation: 
     Complete blood count 
     Routine electrolytes 
     Kidney and liver function tests 
     Lactate dehydrogenase 
     Beta-2 microglobulin 
     Hepatitis B and C serology 
 Bone marrow aspiration and biopsy 
 CT scans of chest/abdomen/pelvis (neck optional) 
Gastric MALT Helicobacter pylori serology (if H pylori not yet confirmed) 
 H pylori stool antigen test (if H pylori not yet confirmed) 
 Endoscopic ultrasound 
 t(11;18) evaluation by FISH 
Nongastric MALT Consider the following based upon history and physical: 
     Upper and lower endoscopy 
     Double contrast radiograph of small bowel 
     Camera endoscopy 
     Endoscopic otolaryngology examination 
     MRI orbit 
     CT scan of parotid/salivary glands 
All patients Diagnostic biopsy (fine needle aspiration 
 [FNA] is not sufficient) 
 Complete history and physical examination 
 Laboratory evaluation: 
     Complete blood count 
     Routine electrolytes 
     Kidney and liver function tests 
     Lactate dehydrogenase 
     Beta-2 microglobulin 
     Hepatitis B and C serology 
 Bone marrow aspiration and biopsy 
 CT scans of chest/abdomen/pelvis (neck optional) 
Gastric MALT Helicobacter pylori serology (if H pylori not yet confirmed) 
 H pylori stool antigen test (if H pylori not yet confirmed) 
 Endoscopic ultrasound 
 t(11;18) evaluation by FISH 
Nongastric MALT Consider the following based upon history and physical: 
     Upper and lower endoscopy 
     Double contrast radiograph of small bowel 
     Camera endoscopy 
     Endoscopic otolaryngology examination 
     MRI orbit 
     CT scan of parotid/salivary glands 

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