Cross-reactivity of cefotetan and ceftriaxone antibodies with various cephalosporins and penicillin.33 Positive results are shown in bold.
| . | Cefotetan antibody . | Ceftriaxone antibody . | |
|---|---|---|---|
| Drug . | A* . | B** . | B** . |
| *A: Serum (anti-cefotetan) tested against drug-coated RBCs | |||
| **B: Serum (anti-cefotetan and anti-ceftriaxone) tested against enzyme-treated group O RBCs in the presence of drugs (1 mg/mL) | |||
| †Titer for cefotetan antibody results are given as hemolysis/ antiglobulin test titer; for ceftriaxone antibody, hemolysis/37°C agglutination/antiglobulin test titers | |||
| Cefotetan | 200,000 | 20/10,240 † | 0/0/0 |
| Ceftriaxone | <10 | 0/0 | 80/5,120/640† |
| Cefamandole | 4 0 | 0/0 | 0/1/1 |
| Cefazolin | <10 | 0/0 | 0/0/0 |
| Cefepime | 2 0 | 0/0 | 0/0/0 |
| Cefoperazone | <10 | 0/0 | 0/1/0 |
| Cefotaxime | 2 0 | 0/0 | 1/1/1 |
| Cefoxitin | 5120 | 0/0 | 0/0/0 |
| Ceftazidime | <10 | 0/0 | 0/0/0 |
| Cephalothin | 5120 | 0/1 | 0/0/0 |
| Penicillin | 320 | 0/0 | 0/0/0 |
| . | Cefotetan antibody . | Ceftriaxone antibody . | |
|---|---|---|---|
| Drug . | A* . | B** . | B** . |
| *A: Serum (anti-cefotetan) tested against drug-coated RBCs | |||
| **B: Serum (anti-cefotetan and anti-ceftriaxone) tested against enzyme-treated group O RBCs in the presence of drugs (1 mg/mL) | |||
| †Titer for cefotetan antibody results are given as hemolysis/ antiglobulin test titer; for ceftriaxone antibody, hemolysis/37°C agglutination/antiglobulin test titers | |||
| Cefotetan | 200,000 | 20/10,240 † | 0/0/0 |
| Ceftriaxone | <10 | 0/0 | 80/5,120/640† |
| Cefamandole | 4 0 | 0/0 | 0/1/1 |
| Cefazolin | <10 | 0/0 | 0/0/0 |
| Cefepime | 2 0 | 0/0 | 0/0/0 |
| Cefoperazone | <10 | 0/0 | 0/1/0 |
| Cefotaxime | 2 0 | 0/0 | 1/1/1 |
| Cefoxitin | 5120 | 0/0 | 0/0/0 |
| Ceftazidime | <10 | 0/0 | 0/0/0 |
| Cephalothin | 5120 | 0/1 | 0/0/0 |
| Penicillin | 320 | 0/0 | 0/0/0 |