Table 4.

Causes of treatment failure and relapse in aplastic anemia.

CausePossible Etiology
Exhaustion of stem cell reserves Immune mediated aplastic anemia 
Insufficient immunosuppression Persistent immune attacks 
Misdiagnosis 
Hereditary bone marrow failure Non-immune pathogenesis 
CausePossible Etiology
Exhaustion of stem cell reserves Immune mediated aplastic anemia 
Insufficient immunosuppression Persistent immune attacks 
Misdiagnosis 
Hereditary bone marrow failure Non-immune pathogenesis 
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