Nucleoside combination chemotherapy regimens for relapsed chronic lymphoblastic leukemia (CLL).
| Regimen . | No. of Patients . | CR (%) . | ORR (%) . |
|---|---|---|---|
| Abbreviations: CR, complete remission ORR, overall response. | |||
| Fudarabine and cyclophosphamide21 | |||
| Alykylator only | 20 | 15 | 85 |
| Alkylator and fludarabine (relapsed after last therapy) | 46 | 13 | 51 |
| Alkylator and fludarabine (refractory to last therapy) | 28 | 3 | 39 |
| Deoxycoformycin and cyclophosphamide22 | 23 | 17 | 74 |
| Fludarabine, cyclophosphamide and mitoxantrone)23 | 37 | 50 | 78 |
| Regimen . | No. of Patients . | CR (%) . | ORR (%) . |
|---|---|---|---|
| Abbreviations: CR, complete remission ORR, overall response. | |||
| Fudarabine and cyclophosphamide21 | |||
| Alykylator only | 20 | 15 | 85 |
| Alkylator and fludarabine (relapsed after last therapy) | 46 | 13 | 51 |
| Alkylator and fludarabine (refractory to last therapy) | 28 | 3 | 39 |
| Deoxycoformycin and cyclophosphamide22 | 23 | 17 | 74 |
| Fludarabine, cyclophosphamide and mitoxantrone)23 | 37 | 50 | 78 |