Table 1.

Potential anti-atherogenic activities of peroxisome proliferator-activated receptors (PPARs).

  1. Increased nitric oxide synthesis and release

  2. Decreased recruitment of T cells

  3. Reduced angiogenesis

  4. Inhibition of smooth muscle cell (SMC) migration

  5. Decreased SMC expression of matrix-degrading enzymes

  6. Decreased macrophage-dependent expression of matrix metalloproteinase (MMP)-9 and osteopontin

  7. Enhanced release of the interleukin-1 receptor antagonist

  8. Enhanced reverse cholesterol transport

 

  1. Increased nitric oxide synthesis and release

  2. Decreased recruitment of T cells

  3. Reduced angiogenesis

  4. Inhibition of smooth muscle cell (SMC) migration

  5. Decreased SMC expression of matrix-degrading enzymes

  6. Decreased macrophage-dependent expression of matrix metalloproteinase (MMP)-9 and osteopontin

  7. Enhanced release of the interleukin-1 receptor antagonist

  8. Enhanced reverse cholesterol transport

 
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