Table 3

Leukapheresis in pregnancy: outcome of patients at Hammersmith Hospital

CML individual pregnancy managed by leukapheresisWCC at diagnosis, ×109/LLeukapheresis regimenOther treatmentDuration of pregnancy,* wkLive infant
  1-2 weekly until 26-30 wk, n = 7 None,
n = 10 
 Live infant,
n = 11 
   
   
N = 1265  25-240 (90) 1-4 × wk, n = 1 HU from 30 wk,
n = 1 
35-40 (39) Live infant, meningomyelocele and talipes,
n = 1 
   
  2-3 × wk, n = 4 Aspirin and LMWH,
n = 1 
  
    
CML individual pregnancy managed by leukapheresisWCC at diagnosis, ×109/LLeukapheresis regimenOther treatmentDuration of pregnancy,* wkLive infant
  1-2 weekly until 26-30 wk, n = 7 None,
n = 10 
 Live infant,
n = 11 
   
   
N = 1265  25-240 (90) 1-4 × wk, n = 1 HU from 30 wk,
n = 1 
35-40 (39) Live infant, meningomyelocele and talipes,
n = 1 
   
  2-3 × wk, n = 4 Aspirin and LMWH,
n = 1 
  
    

HU, hydroxyurea; LMWH, low-molecular-weight heparin; WCC, white cell count.

*

Data not known in 1 case.

Treatment with leukapheresis only.