D-FISH results for LTC-IC experiments with CD34+ CML samples
| UPN . | BCR-ABL-positive/total cells (%) . | ||||||
|---|---|---|---|---|---|---|---|
| Baseline . | No drug . | IM . | Dasatinib . | BMS-214662 . | BMS-214662 + IM . | BMS-214662 + dasatinib . | |
| 166 | 439/463 (95) | 111/111 (100) | ND | 74/74 (100) | 97/99 (98) | ND | 62/62 (100) |
| 189 | 932/1003 (93) | 51/78 (65) | 85/120 (71) | 181/291 (62) | 12/145 (8) | 8/88 (9) | 0/335 (0) |
| 215 | 104/109 (95) | 67/71 (94) | 40/40 (100) | 63/66 (95) | 6/134 (4) | ND | ND |
| UPN . | BCR-ABL-positive/total cells (%) . | ||||||
|---|---|---|---|---|---|---|---|
| Baseline . | No drug . | IM . | Dasatinib . | BMS-214662 . | BMS-214662 + IM . | BMS-214662 + dasatinib . | |
| 166 | 439/463 (95) | 111/111 (100) | ND | 74/74 (100) | 97/99 (98) | ND | 62/62 (100) |
| 189 | 932/1003 (93) | 51/78 (65) | 85/120 (71) | 181/291 (62) | 12/145 (8) | 8/88 (9) | 0/335 (0) |
| 215 | 104/109 (95) | 67/71 (94) | 40/40 (100) | 63/66 (95) | 6/134 (4) | ND | ND |
Colonies were harvested after LTC-IC experiments, pooled for each treatment condition and then FISH was performed on the cells from these colonies.
UPN indicates unique patient number; and ND, not determined.