Outcome data according to FLT3/ITD mutant level
| FLT3 . | WT, % . | ITD low, % . | ITD int., % . | ITD high, % . | OR (CI) . | P . |
|---|---|---|---|---|---|---|
| CR | 84 | 82 | 83 | 85 | 1.00 (0.85-1.17) | 1.0 |
| RD | 10 | 11 | 10 | 8 | 0.97 (0.79-1.19) | .7 |
| ID | 6 | 7 | 7 | 8 | 1.04 (0.82-1.33) | .7 |
| OS at 5 y | 42 | 31 | 28 | 15 | 1.24 (1.16-1.33) | <.001 |
| DFS at 5 y | 41 | 26 | 27 | 16 | 1.28 (1.19-1.38) | <.001 |
| RR at 5 y | 49 | 69 | 64 | 82 | 1.35 (1.24-1.47) | <.001 |
| FLT3 . | WT, % . | ITD low, % . | ITD int., % . | ITD high, % . | OR (CI) . | P . |
|---|---|---|---|---|---|---|
| CR | 84 | 82 | 83 | 85 | 1.00 (0.85-1.17) | 1.0 |
| RD | 10 | 11 | 10 | 8 | 0.97 (0.79-1.19) | .7 |
| ID | 6 | 7 | 7 | 8 | 1.04 (0.82-1.33) | .7 |
| OS at 5 y | 42 | 31 | 28 | 15 | 1.24 (1.16-1.33) | <.001 |
| DFS at 5 y | 41 | 26 | 27 | 16 | 1.28 (1.19-1.38) | <.001 |
| RR at 5 y | 49 | 69 | 64 | 82 | 1.35 (1.24-1.47) | <.001 |
For FLT3 levels, odds ratios (OR) and 95% confidence intervals (CI) were determined by logistic regression.
Int. indicates intermediate mutant level.