Distribution of point mutations in 137 cases with FLT3-TKD mutations
| Amino acid exchange . | No. of patients . | Percentage of patients . |
|---|---|---|
| D835Y | 68 | 49.6 |
| D835H | 20 | 14.6 |
| D835V | 14 | 10.2 |
| D835E | 11 | 8.0 |
| D835A | 3 | 2.2 |
| D835S | 1 | 0.7 |
| D835N | 1 | 0.7 |
| Δ I836 | 14 | 10.2 |
| D835 compound heterozygous | ||
| D835Y + D835E | 2 | 1.4 |
| D835Y + D835A | 1 | 0.7 |
| D835Y + D835H | 1 | 0.7 |
| D835 total | 122 | 89.1 |
| D835V and Δ I836 | 1 | 0.7 |
| Total | 137 | 100.0 |
| Amino acid exchange . | No. of patients . | Percentage of patients . |
|---|---|---|
| D835Y | 68 | 49.6 |
| D835H | 20 | 14.6 |
| D835V | 14 | 10.2 |
| D835E | 11 | 8.0 |
| D835A | 3 | 2.2 |
| D835S | 1 | 0.7 |
| D835N | 1 | 0.7 |
| Δ I836 | 14 | 10.2 |
| D835 compound heterozygous | ||
| D835Y + D835E | 2 | 1.4 |
| D835Y + D835A | 1 | 0.7 |
| D835Y + D835H | 1 | 0.7 |
| D835 total | 122 | 89.1 |
| D835V and Δ I836 | 1 | 0.7 |
| Total | 137 | 100.0 |