Table 1.

Linear regression with accounting for clustering of observations by patient




Full-scale IQ

Performance IQ

Verbal IQ
Variable
No. observations (no. patients)
Coef.
P
Coef.
P
Coef.
P
Age, y   37 (24)   0.047   .51   0.058   .36   0.013   .89  
CBF, mL/100 g/min        
Anterior   19 (16)   −0.13   .30   −0.14   .01   −0.09   .25  
Left   19 (16)   −0.14   .07   −0.15   .02   −0.09   .34  
Right   19 (16)   −0.13   .04   −0.14   .01   −0.09   .27  
Total   19 (16)   −0.14   .05   −0.15   .01   −0.09   .30  
PCV, %   37 (24)   1.2   .21   0.34   .73   1.65   .07  
Platelets, per 109/L   35 (23)   −0.01   .37   −0.003   .85   −0.02   .10  
WBC count, per 109/L   35 (23)   −1.4   .05   −0.8   .21   −1.6   .04  
Maximum CBFV   36 (24)   0.57   .82   2.0   .40   −0.56   .85  
Hemoglobin F
 
30 (22)
 
0.33
 
.53
 
0.02
 
.96
 
0.53
 
.42
 



Full-scale IQ

Performance IQ

Verbal IQ
Variable
No. observations (no. patients)
Coef.
P
Coef.
P
Coef.
P
Age, y   37 (24)   0.047   .51   0.058   .36   0.013   .89  
CBF, mL/100 g/min        
Anterior   19 (16)   −0.13   .30   −0.14   .01   −0.09   .25  
Left   19 (16)   −0.14   .07   −0.15   .02   −0.09   .34  
Right   19 (16)   −0.13   .04   −0.14   .01   −0.09   .27  
Total   19 (16)   −0.14   .05   −0.15   .01   −0.09   .30  
PCV, %   37 (24)   1.2   .21   0.34   .73   1.65   .07  
Platelets, per 109/L   35 (23)   −0.01   .37   −0.003   .85   −0.02   .10  
WBC count, per 109/L   35 (23)   −1.4   .05   −0.8   .21   −1.6   .04  
Maximum CBFV   36 (24)   0.57   .82   2.0   .40   −0.56   .85  
Hemoglobin F
 
30 (22)
 
0.33
 
.53
 
0.02
 
.96
 
0.53
 
.42
 

CBFV indicates cerebral blood flow velocity (z score); Coef., coefficient.

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