Changes in QT intervals and heart rate variability during oral As2O3 therapy
. | As2O3-ON . | As2O3-OFF . | P . |
|---|---|---|---|
| 12-lead ECG | |||
| QT, ms | 383 ± 8 | 359 ± 8 | .08 |
| QTc, ms | 455 ± 6 | 423 ± 7 | < .01 |
| QT dispersion | 54 ± 4 | 54 ± 4 | .82 |
| QTc dispersion | 65 ± 5 | 62 ± 6 | .78 |
| Holter recording | |||
| SDNN, ms | 90 ± 11 | 118 ± 12 | .02 |
| LF, normalized units | 26 ± 2 | 26 ± 2 | .97 |
| HF, normalized units | 22 ± 3 | 24 ± 3 | .21 |
| LF/HF ratio | 1.36 ± 0.16 | 1.45 ± 0.16 | .30 |
. | As2O3-ON . | As2O3-OFF . | P . |
|---|---|---|---|
| 12-lead ECG | |||
| QT, ms | 383 ± 8 | 359 ± 8 | .08 |
| QTc, ms | 455 ± 6 | 423 ± 7 | < .01 |
| QT dispersion | 54 ± 4 | 54 ± 4 | .82 |
| QTc dispersion | 65 ± 5 | 62 ± 6 | .78 |
| Holter recording | |||
| SDNN, ms | 90 ± 11 | 118 ± 12 | .02 |
| LF, normalized units | 26 ± 2 | 26 ± 2 | .97 |
| HF, normalized units | 22 ± 3 | 24 ± 3 | .21 |
| LF/HF ratio | 1.36 ± 0.16 | 1.45 ± 0.16 | .30 |
For the purposes of this table, P values greater than .05 are not significant.
LF, low frequency; HF indicates high frequency; SDNN, standard deviation of normal to normal RR interval.