Patient characteristics and outcomes for UBM or TCD transplants
. | UBM . | TCD . | P . |
---|---|---|---|
Patient and transplant characteristics | |||
No. patients | 37 | 40 | |
Mean age, y, (range) at transplantation | 37 (11-54) | 35 (13-52) | .62 |
Men, % | 68 | 58 | .19 |
Mean Karnofsky performance status score at conditioning | 91 | 91 | .55 |
KIR mismatch with donor, % | 11 | 13 | .83 |
6/6 HLA match with donor, % | 76 | 58 | .01 |
Cyclosporin acute GVHD prophylaxis, % | 81 | 70 | .10 |
Date of transplantation, median (range) | Apr 1995 (1990-1999) | Nov 1995 (1990-1999) | .70 |
Mean time from diagnosis to transplantation, mo | 25 | 27 | .66 |
Transplantation at first chronic phase, % | 73 | 63 | .13 |
Preparative regimen | .49 | ||
Cytoxan and total body irradiation, % | 78 | 85 | |
Cytoxan and busulfan, % | 14 | 10 | |
Other, % | 8 | 5 | |
Treatments and outcomes | |||
Acute GVHD any, % | 78 | 68 | .15 |
Acute GVHD grade II–IV, % | 73 | 45 | < .001 |
Systemic steroids for acute GVHD treatment, % | 70 | 65 | .55 |
Chronic GVHD, % | 65 | 45 | .007 |
Relapse, % | 19 | 30 | .10 |
5-y survival, % | 54 | 52 | .89 |
. | UBM . | TCD . | P . |
---|---|---|---|
Patient and transplant characteristics | |||
No. patients | 37 | 40 | |
Mean age, y, (range) at transplantation | 37 (11-54) | 35 (13-52) | .62 |
Men, % | 68 | 58 | .19 |
Mean Karnofsky performance status score at conditioning | 91 | 91 | .55 |
KIR mismatch with donor, % | 11 | 13 | .83 |
6/6 HLA match with donor, % | 76 | 58 | .01 |
Cyclosporin acute GVHD prophylaxis, % | 81 | 70 | .10 |
Date of transplantation, median (range) | Apr 1995 (1990-1999) | Nov 1995 (1990-1999) | .70 |
Mean time from diagnosis to transplantation, mo | 25 | 27 | .66 |
Transplantation at first chronic phase, % | 73 | 63 | .13 |
Preparative regimen | .49 | ||
Cytoxan and total body irradiation, % | 78 | 85 | |
Cytoxan and busulfan, % | 14 | 10 | |
Other, % | 8 | 5 | |
Treatments and outcomes | |||
Acute GVHD any, % | 78 | 68 | .15 |
Acute GVHD grade II–IV, % | 73 | 45 | < .001 |
Systemic steroids for acute GVHD treatment, % | 70 | 65 | .55 |
Chronic GVHD, % | 65 | 45 | .007 |
Relapse, % | 19 | 30 | .10 |
5-y survival, % | 54 | 52 | .89 |