Risk factors associated with decreased event-free survival
. | Entire cohort . | . | Standard risk . | . | High risk . | . | |||
|---|---|---|---|---|---|---|---|---|---|
| Risk factor . | Relative risk . | P . | Relative risk . | P . | Relative risk . | P . | |||
| Down syndrome | |||||||||
| No | 1.0 | 1.0 | 1.0 | ||||||
| Yes | 1.5 | <.001 | 2.0 | <.001 | 1.1 | .8 | |||
| Sex | |||||||||
| Male | 1.0 | 1.0 | 1.0 | ||||||
| Female | 0.9 | <.001 | 0.8 | .002 | 0.9 | .009 | |||
| Age | |||||||||
| 1 y to 9 y | 1.0 | 1.0 | |||||||
| Less than 1 y | 3.4 | <.001 | 3.5 | <.001 | |||||
| 10 y or more | 1.7 | <.001 | 1.8 | <.001 | |||||
| White blood cell count at diagnosis, Less than 50 × 109/L | 1.0 | 1.0 | |||||||
| At least 50 × 109/L | 1.4 | <.001 | 1.5 | <.001 | |||||
| Race | |||||||||
| White | 1.0 | 1.0 | 1.0 | ||||||
| Asian | 0.8 | .2 | 1.98 | <.001 | 0.6 | .06 | |||
| Black | 1.4 | <.001 | 1.2 | .1 | 1.1 | .2 | |||
| Hispanic | 1.3 | <.001 | 1.0 | .9 | 1.4 | <.001 | |||
| Spleen size | |||||||||
| Normal | 1.0 | 1.0 | 1.0 | ||||||
| Enlarged | 1.2 | .002 | 1.2 | .006 | 1.1 | .1 | |||
| Liver size | |||||||||
| Normal | 1.0 | 1.0 | 1.0 | ||||||
| Enlarged | 1.2 | <.001 | 1.2 | .007 | 1.2 | .006 | |||
. | Entire cohort . | . | Standard risk . | . | High risk . | . | |||
|---|---|---|---|---|---|---|---|---|---|
| Risk factor . | Relative risk . | P . | Relative risk . | P . | Relative risk . | P . | |||
| Down syndrome | |||||||||
| No | 1.0 | 1.0 | 1.0 | ||||||
| Yes | 1.5 | <.001 | 2.0 | <.001 | 1.1 | .8 | |||
| Sex | |||||||||
| Male | 1.0 | 1.0 | 1.0 | ||||||
| Female | 0.9 | <.001 | 0.8 | .002 | 0.9 | .009 | |||
| Age | |||||||||
| 1 y to 9 y | 1.0 | 1.0 | |||||||
| Less than 1 y | 3.4 | <.001 | 3.5 | <.001 | |||||
| 10 y or more | 1.7 | <.001 | 1.8 | <.001 | |||||
| White blood cell count at diagnosis, Less than 50 × 109/L | 1.0 | 1.0 | |||||||
| At least 50 × 109/L | 1.4 | <.001 | 1.5 | <.001 | |||||
| Race | |||||||||
| White | 1.0 | 1.0 | 1.0 | ||||||
| Asian | 0.8 | .2 | 1.98 | <.001 | 0.6 | .06 | |||
| Black | 1.4 | <.001 | 1.2 | .1 | 1.1 | .2 | |||
| Hispanic | 1.3 | <.001 | 1.0 | .9 | 1.4 | <.001 | |||
| Spleen size | |||||||||
| Normal | 1.0 | 1.0 | 1.0 | ||||||
| Enlarged | 1.2 | .002 | 1.2 | .006 | 1.1 | .1 | |||
| Liver size | |||||||||
| Normal | 1.0 | 1.0 | 1.0 | ||||||
| Enlarged | 1.2 | <.001 | 1.2 | .007 | 1.2 | .006 | |||