Thrombosis risk for fibrinogen γ′ levels and total fibrinogen levels
. | ORadj (95% CI) . | . | . | ||
|---|---|---|---|---|---|
. | A . | B . | C . | ||
| Fibrinogen γ′ levels | |||||
| More than 132 | 1* | 1* | 1* | ||
| 109-132 | 1.2 (0.8-1.8) | 1.2 (0.8-1.9) | 1.5 (1.0-2.4) | ||
| 86-109 | 1.9 (1.2-3.0) | 1.9 (1.1-3.0) | 2.3 (1.3-4.0) | ||
| Less than 86 | 3.0 (1.8-4.9) | 2.9 (1.6-5.4) | 3.6 (1.9-7.0) | ||
| Total fibrinogen levels | |||||
| Less than 101 | 1* | 1* | 1* | ||
| 101-114 | 1.1 (0.7-1.6) | 1.0 (0.7-1.5) | 0.9 (0.6-1.4) | ||
| 114-130 | 1.6 (1.1-2.5) | 1.6 (1.0-2.4) | 1.4 (0.9-2.2) | ||
| More than 130 | 3.2 (2.0-5.2) | 3.2 (1.8-5.4) | 2.2 (1.2-4.0) | ||
| FGG haplotype 2 | |||||
| HxHx | NA | 1* | 1* | ||
| H2Hx | NA | 0.9 (0.6-1.2) | 0.8 (0.6-1.2) | ||
| H2H2 | NA | 1.4 (0.8-2.5) | 1.3 (0.7-2.4) | ||
. | ORadj (95% CI) . | . | . | ||
|---|---|---|---|---|---|
. | A . | B . | C . | ||
| Fibrinogen γ′ levels | |||||
| More than 132 | 1* | 1* | 1* | ||
| 109-132 | 1.2 (0.8-1.8) | 1.2 (0.8-1.9) | 1.5 (1.0-2.4) | ||
| 86-109 | 1.9 (1.2-3.0) | 1.9 (1.1-3.0) | 2.3 (1.3-4.0) | ||
| Less than 86 | 3.0 (1.8-4.9) | 2.9 (1.6-5.4) | 3.6 (1.9-7.0) | ||
| Total fibrinogen levels | |||||
| Less than 101 | 1* | 1* | 1* | ||
| 101-114 | 1.1 (0.7-1.6) | 1.0 (0.7-1.5) | 0.9 (0.6-1.4) | ||
| 114-130 | 1.6 (1.1-2.5) | 1.6 (1.0-2.4) | 1.4 (0.9-2.2) | ||
| More than 130 | 3.2 (2.0-5.2) | 3.2 (1.8-5.4) | 2.2 (1.2-4.0) | ||
| FGG haplotype 2 | |||||
| HxHx | NA | 1* | 1* | ||
| H2Hx | NA | 0.9 (0.6-1.2) | 0.8 (0.6-1.2) | ||
| H2H2 | NA | 1.4 (0.8-2.5) | 1.3 (0.7-2.4) | ||
All levels are measured in units per deciliter.
A, logistic regression using quartiles of fibrinogen γ′ and total fibrinogen.
B, logistic regression using quartiles of fibrinogen γ′, total fibrinogen, and FGG-H2 genotypes.
C, logistic regression using quartiles of fibrinogen γ′, total fibrinogen, and FGG-H2 genotypes, adjusted for age, sex, diabetes mellitus, BMI, and high levels (higher than P90) of prothrombin, factor VIII, factor IX, factor XI, and CRP.
NA indicates not applicable.
Reference category