Response rates for CHOP and R-CHOP
. | CHOP . | R-CHOP . |
|---|---|---|
| Patients, n | ||
| Documented | 205 | 223 |
| Evaluable | 205 | 222 |
| Remission | ||
| CR, n (%) | 35 (17) | 44 (2) |
| PR, n (%) | 150 (73) | 170 (77) |
| Overall response, CR + PR, n (%; 95% CI) | 185 (90;85-94) | 214 (96;93-98) |
| Minor response or stable disease, n (%) | 11 (5) | 4 (2) |
| Disease progression during therapy, n (%) | 7 (3) | 2 (1) |
| Death during therapy, n (%) | 2 (1) | 2 (1) |
. | CHOP . | R-CHOP . |
|---|---|---|
| Patients, n | ||
| Documented | 205 | 223 |
| Evaluable | 205 | 222 |
| Remission | ||
| CR, n (%) | 35 (17) | 44 (2) |
| PR, n (%) | 150 (73) | 170 (77) |
| Overall response, CR + PR, n (%; 95% CI) | 185 (90;85-94) | 214 (96;93-98) |
| Minor response or stable disease, n (%) | 11 (5) | 4 (2) |
| Disease progression during therapy, n (%) | 7 (3) | 2 (1) |
| Death during therapy, n (%) | 2 (1) | 2 (1) |
R-CHOP resulted in a significantly higher overall response rate (CR and PR) of 96% compared with 90% for CHOP (P = .011); differences in the CR rate were not statistically significant. 95% CI indicates 95% confidence interval.