Table 4.

Multivariable analysis on predictors of OS and EFS

VariableOSEFS
HR95% CIP valueHR95% CIP value
Pre-HSCT status       
Age at HSCT 1.10 0.91-1.36 .332 1.09 0.94-1.30 .276 
Bronchiectasis 1.06 0.08-13.8 .962 1.15 0.10-9.7 .899 
Pneumatocele 0.88 0.04-13.6 .923 0.54 0.05-4.0 .560 
Pulmonary fungal infection 2.56 0.21-45.3 .463 1.44 0.14-14.2 .744 
Donor       
Matched family 1.00      
Matched unrelated 2.47 0.06-163 .642 7.85 0.49-207 .162 
Graft source       
Marrow 1.00      
PBSC 0.13 <0.01-3.10 .280 0.55 0.0-6.47 .655 
Conditioning       
Treosulfan 1.00   1.00   
Busulfan 0.92 0.03-19.5 .956 3.81 0.26-50.4 .362 
Melphalan 0.85 0.02-17.3 .915 1.10 0.09-14.3 .937 
VariableOSEFS
HR95% CIP valueHR95% CIP value
Pre-HSCT status       
Age at HSCT 1.10 0.91-1.36 .332 1.09 0.94-1.30 .276 
Bronchiectasis 1.06 0.08-13.8 .962 1.15 0.10-9.7 .899 
Pneumatocele 0.88 0.04-13.6 .923 0.54 0.05-4.0 .560 
Pulmonary fungal infection 2.56 0.21-45.3 .463 1.44 0.14-14.2 .744 
Donor       
Matched family 1.00      
Matched unrelated 2.47 0.06-163 .642 7.85 0.49-207 .162 
Graft source       
Marrow 1.00      
PBSC 0.13 <0.01-3.10 .280 0.55 0.0-6.47 .655 
Conditioning       
Treosulfan 1.00   1.00   
Busulfan 0.92 0.03-19.5 .956 3.81 0.26-50.4 .362 
Melphalan 0.85 0.02-17.3 .915 1.10 0.09-14.3 .937 

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