Table 3.

Univariate analysis on predictors of OS and EFS

VariableOSEFS
HR95% CIP valueHR95% CIP value
Pre-HSCT status       
Age at HSCT 1.05 0.91-1.15 .402 1.03 0.93-1.11 .453 
Bronchiectasis 1.78 0.21-14.8 .563 0.94 0.13-4.81 .942 
Pneumatocele 0.80 0.09-6.66 .821 0.84 0.15-4.68 .838 
Any parenchymal lung disease 1.21 0.16-24.5 .868 0.82 0.16-5.98 .820 
Pulmonary fungal infection 2.05 0.24-17.1 .472 1.30 0.18-6.69 .760 
Donor       
Matched family 1.00      
Matched unrelated 0.81 0.09-6.71 .829 2.01 0.41-15.0 .396 
Graft source       
Marrow 1.00      
PBSC 0.29 0.01-2.24 .279 1.08 0.19-5.94 .927 
Conditioning       
Treosulfan 1.00      
Busulfan 0.98 0.05-10.2 .985 1.86 0.22-15.8 .541 
Melphalan 1.44 0.07-15.0 .768 1.98 0.22-17.1 .507 
Serotherapy       
Alemtuzumab 1.00      
ATG <0.01 <0.01-2.22 >.99 0.61 0.03-4.16 .662 
VariableOSEFS
HR95% CIP valueHR95% CIP value
Pre-HSCT status       
Age at HSCT 1.05 0.91-1.15 .402 1.03 0.93-1.11 .453 
Bronchiectasis 1.78 0.21-14.8 .563 0.94 0.13-4.81 .942 
Pneumatocele 0.80 0.09-6.66 .821 0.84 0.15-4.68 .838 
Any parenchymal lung disease 1.21 0.16-24.5 .868 0.82 0.16-5.98 .820 
Pulmonary fungal infection 2.05 0.24-17.1 .472 1.30 0.18-6.69 .760 
Donor       
Matched family 1.00      
Matched unrelated 0.81 0.09-6.71 .829 2.01 0.41-15.0 .396 
Graft source       
Marrow 1.00      
PBSC 0.29 0.01-2.24 .279 1.08 0.19-5.94 .927 
Conditioning       
Treosulfan 1.00      
Busulfan 0.98 0.05-10.2 .985 1.86 0.22-15.8 .541 
Melphalan 1.44 0.07-15.0 .768 1.98 0.22-17.1 .507 
Serotherapy       
Alemtuzumab 1.00      
ATG <0.01 <0.01-2.22 >.99 0.61 0.03-4.16 .662 

CI, confidence interval; HR, hazard ratio.

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