Table 2.

HSCT characteristics

Time period of HSCT  
<2010 5 (12.2) 
≥2010 36 (87.8) 
Donor type  
Matched family 18 (43.9) 
Matched unrelated 18 (43.9) 
Mismatched related 4 (9.8) 
Mismatched unrelated 1 (2.4) 
Stem cell source  
PBSC 21 (51.2) 
Marrow 20 (48.8) 
Conditioning  
Treosulfan-based (42 g/m224 (58.5), 14 with thiotepa 
Busulfan-based 10 (24.4), AUC targeted in 6 
Melphalan-based 7 (17.1) 
Serotherapy  
Alemtuzumab 22 (53.7) 
ATG 10 (24.4) 
None 9 (21.9) 
GVHD prophylaxis  
CNI + MMF 16 (39.0) 
CNI + methotrexate 7 (17.1) 
CNI alone 7 (17.1) 
PTCy 7 (17.1) 
None 4 (9.8) 
Median CD34+ cell dose, ×106/kg 6.2 (0.05-22.0) 
Time period of HSCT  
<2010 5 (12.2) 
≥2010 36 (87.8) 
Donor type  
Matched family 18 (43.9) 
Matched unrelated 18 (43.9) 
Mismatched related 4 (9.8) 
Mismatched unrelated 1 (2.4) 
Stem cell source  
PBSC 21 (51.2) 
Marrow 20 (48.8) 
Conditioning  
Treosulfan-based (42 g/m224 (58.5), 14 with thiotepa 
Busulfan-based 10 (24.4), AUC targeted in 6 
Melphalan-based 7 (17.1) 
Serotherapy  
Alemtuzumab 22 (53.7) 
ATG 10 (24.4) 
None 9 (21.9) 
GVHD prophylaxis  
CNI + MMF 16 (39.0) 
CNI + methotrexate 7 (17.1) 
CNI alone 7 (17.1) 
PTCy 7 (17.1) 
None 4 (9.8) 
Median CD34+ cell dose, ×106/kg 6.2 (0.05-22.0) 

ATG, antithymocyte globulin; CNI, calcineurin inhibitor; MMF, mycophenolate mofetil; PBSC, peripheral blood stem cell; PTCy, posttransplant cyclophosphamide.

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