AEs
| AE . | Any grade . | Grade 3-4 . |
|---|---|---|
| Hematologic | ||
| Leukopenia | 4 | 1 |
| Neutropenia | 7 | 5 |
| Lymphopenia | 4 | 3 |
| Thrombocytopenia | 6 | 2 |
| Anemia | 2 | 0 |
| Nonhematologic | ||
| Arrythmia (including atrial fibrillation/sinus tachycardia) | 4 | 0 |
| Bloating/abdominal distension | 4 | 0 |
| Blurred vision/cataract | 5 | 1 |
| Constipation | 13 | 1 |
| Creatinine increased | 2 | 0 |
| Diarrhea | 9 | 0 |
| Dizziness | 6 | 0 |
| Dysgeusia | 5 | 0 |
| Dyspnea | 3 | 0 |
| Edema | 13 | 1 |
| Fatigue | 21 | 3 |
| Fever | 2 | 0 |
| Generalized weakness | 3 | 0 |
| Hyperglycemia | 4 | 2 |
| Hypoalbuminemia | 2 | 1 |
| Hypogammaglobulinemia | 1 | 0 |
| Infection, any | 9 | 4 |
| Insomnia | 10 | 0 |
| Mood disturbance/altered mental status | 6 | 0 |
| Muscle weakness/generalized weakness | 6 | 1 |
| Nausea | 12 | 0 |
| Pain | ||
| Back pain | 2 | 0 |
| Abdominal pain (epigastric pain, dyspepsia) | 5 | 0 |
| Musculoskeletal | 3 | 1 |
| Oral pain | 2 | 0 |
| Nasal pain | 1 | 0 |
| Peripheral neuropathy | 15 | 1 |
| Tremor | 3 | 0 |
| Vomiting | 2 | 0 |
| Rash | 4 | 0 |
| Respiratory tract infection | 7 | 3 |
| AE . | Any grade . | Grade 3-4 . |
|---|---|---|
| Hematologic | ||
| Leukopenia | 4 | 1 |
| Neutropenia | 7 | 5 |
| Lymphopenia | 4 | 3 |
| Thrombocytopenia | 6 | 2 |
| Anemia | 2 | 0 |
| Nonhematologic | ||
| Arrythmia (including atrial fibrillation/sinus tachycardia) | 4 | 0 |
| Bloating/abdominal distension | 4 | 0 |
| Blurred vision/cataract | 5 | 1 |
| Constipation | 13 | 1 |
| Creatinine increased | 2 | 0 |
| Diarrhea | 9 | 0 |
| Dizziness | 6 | 0 |
| Dysgeusia | 5 | 0 |
| Dyspnea | 3 | 0 |
| Edema | 13 | 1 |
| Fatigue | 21 | 3 |
| Fever | 2 | 0 |
| Generalized weakness | 3 | 0 |
| Hyperglycemia | 4 | 2 |
| Hypoalbuminemia | 2 | 1 |
| Hypogammaglobulinemia | 1 | 0 |
| Infection, any | 9 | 4 |
| Insomnia | 10 | 0 |
| Mood disturbance/altered mental status | 6 | 0 |
| Muscle weakness/generalized weakness | 6 | 1 |
| Nausea | 12 | 0 |
| Pain | ||
| Back pain | 2 | 0 |
| Abdominal pain (epigastric pain, dyspepsia) | 5 | 0 |
| Musculoskeletal | 3 | 1 |
| Oral pain | 2 | 0 |
| Nasal pain | 1 | 0 |
| Peripheral neuropathy | 15 | 1 |
| Tremor | 3 | 0 |
| Vomiting | 2 | 0 |
| Rash | 4 | 0 |
| Respiratory tract infection | 7 | 3 |