Table 1.

Patient characteristics

VariableTübingenSydney
No. of patients 10 
Sex, (female) 3 (50%) 7 (70%) 
Age, y 36 (20-62) 65 (34-74) 
PLT count (at admission)  42 (14-60) 48 (18-124) 
D-dimer 31 (12.4-73) 40 (19.8-132) 
Mean OD EIA 2.91 (2.07-3.48) 2.46 (1.90-2.95) 
Positive PF4-modified HIPA (Tübingen)/SRA (Sydney) 6 (100%) 10 (100%) 
Vaccine   
AstraZeneca 5 (83%) 10 (100%) 
Johnson & Johnson 1 (17%) 
Days after vaccination 9 (7-28) 10 (4-25) 
Thrombosis 6 (100%) 10 (100%) 
Cerebral venous sinus thrombosis 4 (67%) 2 (20%) 
Splanchnic thrombosis 3 (30%) 
Deep vein thrombosis 6 (60%) 
Pulmonary embolism 1 (17%) 1 (10%) 
Internal jugular vein thrombosis 1 (10%) 
Arterial thrombosis 2 (33%) 
VariableTübingenSydney
No. of patients 10 
Sex, (female) 3 (50%) 7 (70%) 
Age, y 36 (20-62) 65 (34-74) 
PLT count (at admission)  42 (14-60) 48 (18-124) 
D-dimer 31 (12.4-73) 40 (19.8-132) 
Mean OD EIA 2.91 (2.07-3.48) 2.46 (1.90-2.95) 
Positive PF4-modified HIPA (Tübingen)/SRA (Sydney) 6 (100%) 10 (100%) 
Vaccine   
AstraZeneca 5 (83%) 10 (100%) 
Johnson & Johnson 1 (17%) 
Days after vaccination 9 (7-28) 10 (4-25) 
Thrombosis 6 (100%) 10 (100%) 
Cerebral venous sinus thrombosis 4 (67%) 2 (20%) 
Splanchnic thrombosis 3 (30%) 
Deep vein thrombosis 6 (60%) 
Pulmonary embolism 1 (17%) 1 (10%) 
Internal jugular vein thrombosis 1 (10%) 
Arterial thrombosis 2 (33%) 

Continuous variables are expressed as median (range).

EIA, enzyme immune-assay; HIPA, heparin-induced platelet activation assay; OD, optical density; SRA, serotonin-release assay.

Reference range PLT count (150 × 109 to 450 × 109/L).

Upper limit of normal.

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