Baseline characteristics in patients with newly diagnosed plasmacytoma (+) vs true solitary plasmacytoma in our Mayo Clinic cohort
| . | Plasmacytoma (+) (n = 72) . | Solitary plasmacytoma (n = 75) . | Total (N = 147) . | P value . |
|---|---|---|---|---|
| Age, y | .009 | |||
| Median (range) | 63.5 (28.7-83.6) | 56.2 (15.4-82.1) | 60.7 (15.4-83.6) | |
| M-spike, g/dL | .045 | |||
| Not present | 20 (29.4%) | 33 (45.8%) | 53 (37.9%) | |
| Present | 48 (70.6%) | 39 (54.2%) | 87 (62.1%) | |
| Immunoparesis | .184 | |||
| No | 43 (74.1%) | 48 (84.2%) | 91 (79.1%) | |
| Yes | 15 (25.9%) | 9 (15.8%) | 24 (20.9%) | |
| Hemoglobin, g/dL | .533 | |||
| Median (range) | 13.8 (9.6-16.9) | 13.9 (10.5-18.2) | 13.8 (9.6-18.2) | |
| Involved-uninvolved light chain, mg/dL | .880 | |||
| Median (range) | 2.8 (0.1-116.7) | 1.3 (0-106.4) | 2 (0-116.7) | |
| Calcium, mg/dL | .915 | |||
| Median (range) | 9.5 (8.2-10.3) | 9.5 (8-10.7) | 9.5 (8-10.7) | |
| Serum immunofixation | .021 | |||
| Negative | 9 (13.8%) | 21 (30.4%) | 30 (22.4%) | |
| Positive | 56 (86.2%) | 48 (69.6%) | 104 (77.6%) | |
| Urine immunofixation | .193 | |||
| Negative | 18 (34.0%) | 25 (46.3%) | 43 (40.2%) | |
| Positive | 35 (66.0%) | 29 (53.7%) | 64 (59.8%) | |
| Presence of fracture | .225 | |||
| No | 43 (63.2%) | 51 (72.9%) | 94 (68.1%) | |
| Yes | 25 (36.8%) | 19 (27.1%) | 44 (31.9%) | |
| Albumin, mg/dL | .966 | |||
| Median (range) | 3.7 (2.9-4.9) | 3.6 (2.8-5.2) | 3.700 (2.8-5.2) | |
| Location | .092 | |||
| Appendicular | 19 (26.4%) | 19 (25.3%) | 38 (25.9%) | |
| Axial | 50 (69.4%) | 45 (60.0%) | 95 (64.6%) | |
| Extramedullary | 3 (4.2%) | 11 (14.7%) | 14 (9.5%) | |
| Size, cm | .328 | |||
| Median (range) | 4 (0.3-14) | 5.1 (0.3-12) | 4.3 (0.3-14) |
| . | Plasmacytoma (+) (n = 72) . | Solitary plasmacytoma (n = 75) . | Total (N = 147) . | P value . |
|---|---|---|---|---|
| Age, y | .009 | |||
| Median (range) | 63.5 (28.7-83.6) | 56.2 (15.4-82.1) | 60.7 (15.4-83.6) | |
| M-spike, g/dL | .045 | |||
| Not present | 20 (29.4%) | 33 (45.8%) | 53 (37.9%) | |
| Present | 48 (70.6%) | 39 (54.2%) | 87 (62.1%) | |
| Immunoparesis | .184 | |||
| No | 43 (74.1%) | 48 (84.2%) | 91 (79.1%) | |
| Yes | 15 (25.9%) | 9 (15.8%) | 24 (20.9%) | |
| Hemoglobin, g/dL | .533 | |||
| Median (range) | 13.8 (9.6-16.9) | 13.9 (10.5-18.2) | 13.8 (9.6-18.2) | |
| Involved-uninvolved light chain, mg/dL | .880 | |||
| Median (range) | 2.8 (0.1-116.7) | 1.3 (0-106.4) | 2 (0-116.7) | |
| Calcium, mg/dL | .915 | |||
| Median (range) | 9.5 (8.2-10.3) | 9.5 (8-10.7) | 9.5 (8-10.7) | |
| Serum immunofixation | .021 | |||
| Negative | 9 (13.8%) | 21 (30.4%) | 30 (22.4%) | |
| Positive | 56 (86.2%) | 48 (69.6%) | 104 (77.6%) | |
| Urine immunofixation | .193 | |||
| Negative | 18 (34.0%) | 25 (46.3%) | 43 (40.2%) | |
| Positive | 35 (66.0%) | 29 (53.7%) | 64 (59.8%) | |
| Presence of fracture | .225 | |||
| No | 43 (63.2%) | 51 (72.9%) | 94 (68.1%) | |
| Yes | 25 (36.8%) | 19 (27.1%) | 44 (31.9%) | |
| Albumin, mg/dL | .966 | |||
| Median (range) | 3.7 (2.9-4.9) | 3.6 (2.8-5.2) | 3.700 (2.8-5.2) | |
| Location | .092 | |||
| Appendicular | 19 (26.4%) | 19 (25.3%) | 38 (25.9%) | |
| Axial | 50 (69.4%) | 45 (60.0%) | 95 (64.6%) | |
| Extramedullary | 3 (4.2%) | 11 (14.7%) | 14 (9.5%) | |
| Size, cm | .328 | |||
| Median (range) | 4 (0.3-14) | 5.1 (0.3-12) | 4.3 (0.3-14) |