Table 1.

Patient characteristics

AgeDiseaseStage at diagnosisPrevious lines of therapyResponse to previous line of therapyDose level
53 ATLL, acute Ruxolitinib, rhIL-15 with avelumab PR 
62 SS 4B (T4N1M0B2) Bexarotene, extracorporeal photopheresis, interferon alpha, vorinostat, alemtuzumab, mogamulizumab, pembrolizumab + TTI-621, doxil CR 
65 ATLL, acute EPOCH PD 
46 ATLL, lymphomatous CHOP, rhIL-15 with alemtuzumab PD 
30 ATLL, acute CHOP, GDP PD 
63 MF 2A (T2N0M0B0) CHOP, brentuximab vedotin, bendamustine, rhIL-15 with avelumab PD 
AgeDiseaseStage at diagnosisPrevious lines of therapyResponse to previous line of therapyDose level
53 ATLL, acute Ruxolitinib, rhIL-15 with avelumab PR 
62 SS 4B (T4N1M0B2) Bexarotene, extracorporeal photopheresis, interferon alpha, vorinostat, alemtuzumab, mogamulizumab, pembrolizumab + TTI-621, doxil CR 
65 ATLL, acute EPOCH PD 
46 ATLL, lymphomatous CHOP, rhIL-15 with alemtuzumab PD 
30 ATLL, acute CHOP, GDP PD 
63 MF 2A (T2N0M0B0) CHOP, brentuximab vedotin, bendamustine, rhIL-15 with avelumab PD 

CHOP, cyclophosphamide, doxorubicin, vincristine, prednisone; CR, complete response; EPOCH, etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin; GDP, gemcitabine, cisplatin, dexamethasone; PD, progressive disease; PR, partial response.

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