Table 5. Final model performance for... | American Society of Hematology

Table 5.

Final model performance for clinician- and patient-reported 6-month treatment response

	AUC	Cut-point∗	Sensitivity	Specificity	PPV	NPV
Clinician model
Training	0.83	0.47	0.77	0.79	0.75	0.80
Validation	0.75	0.47	0.60	0.79	0.77	0.63
Patient model
Cut-point based on Youden J
Training	0.86	0.63	0.75	0.86	0.86	0.74
Validation	0.75	0.63	0.52	0.84	0.85	0.50
Cut-point based on distance to (1, 1)
Training	0.86	0.54	0.78	0.82	0.84	0.76
Validation	0.75	0.54	0.60	0.78	0.83	0.53

	AUC	Cut-point∗	Sensitivity	Specificity	PPV	NPV
Clinician model
Training	0.83	0.47	0.77	0.79	0.75	0.80
Validation	0.75	0.47	0.60	0.79	0.77	0.63
Patient model
Cut-point based on Youden J
Training	0.86	0.63	0.75	0.86	0.86	0.74
Validation	0.75	0.63	0.52	0.84	0.85	0.50
Cut-point based on distance to (1, 1)
Training	0.86	0.54	0.78	0.82	0.84	0.76
Validation	0.75	0.54	0.60	0.78	0.83	0.53

AUC, area under curve; NPV, negative predictive value; PPV, positive predictive value.

Based on Youden J and distance to (1, 1)