Table 1.

Effect of mAb R21D10 on EDTA-induced dissociation of αIIbβ3 as measured by the αIIbβ3 complex–specific mAb 10E5

Mean fluorescence intensity
(mean ± standard deviation)
No EDTA  
Buffer 8056 ± 565 
Unlabeled 10E5 137 ± 15 
With EDTA  
Buffer 599 ± 144 
R21D10 1049 ± 240  
7H2  278 
Mean fluorescence intensity
(mean ± standard deviation)
No EDTA  
Buffer 8056 ± 565 
Unlabeled 10E5 137 ± 15 
With EDTA  
Buffer 599 ± 144 
R21D10 1049 ± 240  
7H2  278 

P = .0318 compare with EDTA-treated platelets with buffer.

Values shown are based on 4 different experiments, except for data with mAb 7H2, in which the average of 2 experiments is shown.

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