Table 6. Age-adjusted incidence rates of... | American Society of Hematology

Table 6.

Age-adjusted incidence rates of malignancies in donors compared with the US general population: PBSC donors vs US general population (SEER)

Outcomes	PBSC donors			US general population (SEER)			Rate ratio (95% CI)	P value
Outcomes	Person, -years	No. of events	Incidence rate∗ (95% CI)	Person-years	No. of events	Incidence rate∗ (95% CI)	Rate ratio (95% CI)	P value
Myeloid	118 712	3	2.53 (0.82-7.84)	2 211 987 365	396 134	17.91 (17.85-17.96)	0.14 (0.05-0.44)	<.001†
Lymphoid	118 649	17	14.33 (8.91-23.05)	2 211 987 365	746 740	33.76 (33.68-33.84)	0.42 (0.26-0.68)	<.001†
Other malignancies	116 213	535	460.36 (423.0-501.0)	2 211 987 365	12 569 821	568.3 (567.9-568.6)	0.81 (0.74-0.88)	<.001†

Outcomes	PBSC donors			US general population (SEER)			Rate ratio (95% CI)	P value
Outcomes	Person, -years	No. of events	Incidence rate∗ (95% CI)	Person-years	No. of events	Incidence rate∗ (95% CI)	Rate ratio (95% CI)	P value
Myeloid	118 712	3	2.53 (0.82-7.84)	2 211 987 365	396 134	17.91 (17.85-17.96)	0.14 (0.05-0.44)	<.001†
Lymphoid	118 649	17	14.33 (8.91-23.05)	2 211 987 365	746 740	33.76 (33.68-33.84)	0.42 (0.26-0.68)	<.001†
Other malignancies	116 213	535	460.36 (423.0-501.0)	2 211 987 365	12 569 821	568.3 (567.9-568.6)	0.81 (0.74-0.88)	<.001†

CI, Confidence Interval

Age-adjusted incidence rate per 100 000 person-years.

Result is statistically significant (P < .05).