Table 1.

Patient characteristics

n (%)
Age, y (mean ± SD) 29.7 ± 10.2 
Female 54 (56) 
Hypertension 3 (3) 
Diabetes mellitus 1 (1) 
Current smoking 1 (2) 
Dyslipidemia 0 (0) 
Epileptic seizures 8 (8) 
Headaches 22 (23) 
Previously suspected TIA 4 (4) 
Previously known stroke 41 (42)  
Ischemic 38 (40) 
Hemorrhagic 4 (4) 
Previously suspected or known intracranial vasculopathy 60 (61) 
Genotype  
SS 91 (95) 
Sβ 2 (2) 
SC 3 (3) 
Treatment  
Blood exchange transfusion (±hydroxyurea) 61 (63) 
Hydroxyurea only 25 (26) 
Cerebral revascularization 6 (6) 
None 10 (10) 
EL  
Grade 1 (education stopped before the ninth grade) 10 (10) 
Grade 2 (education stopped before the 12th grade) 34 (35) 
Grade 3 (education “after high school”) 52 (54) 
CE  
France (since preschool, 3) 66 (69) 
France (since primary school, 2) 6 (6) 
Other (1) 22 (23) 
Unknown 2 (2) 
Cognitive complaint  
Absent 43 (45) 
Present 51 (53) 
Unknown 2 (2) 
n (%)
Age, y (mean ± SD) 29.7 ± 10.2 
Female 54 (56) 
Hypertension 3 (3) 
Diabetes mellitus 1 (1) 
Current smoking 1 (2) 
Dyslipidemia 0 (0) 
Epileptic seizures 8 (8) 
Headaches 22 (23) 
Previously suspected TIA 4 (4) 
Previously known stroke 41 (42)  
Ischemic 38 (40) 
Hemorrhagic 4 (4) 
Previously suspected or known intracranial vasculopathy 60 (61) 
Genotype  
SS 91 (95) 
Sβ 2 (2) 
SC 3 (3) 
Treatment  
Blood exchange transfusion (±hydroxyurea) 61 (63) 
Hydroxyurea only 25 (26) 
Cerebral revascularization 6 (6) 
None 10 (10) 
EL  
Grade 1 (education stopped before the ninth grade) 10 (10) 
Grade 2 (education stopped before the 12th grade) 34 (35) 
Grade 3 (education “after high school”) 52 (54) 
CE  
France (since preschool, 3) 66 (69) 
France (since primary school, 2) 6 (6) 
Other (1) 22 (23) 
Unknown 2 (2) 
Cognitive complaint  
Absent 43 (45) 
Present 51 (53) 
Unknown 2 (2) 

N = 96 patients.

SD, standard deviation; TIA, transient ischemic attack.

One patient had both an ischemic and an hemorrhagic stroke history.

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