AEs with fostamatinib
| Variable . | n (%) . |
|---|---|
| Any adverse event | 94 (100) |
| Number of grade 3-4 events | 13 (13.8) |
| Diarrhea | 28 (29.8) |
| Hypertension | 21 (22.3) |
| Neutropenia grade 3-4 | 10 (10.6) |
| Headaches | 8 (8.5) |
| Hepatobiliary laboratory abnormalities | 7 (7.4) |
| Dyspepsia/epigastralgia | 4 (4.25) |
| Depression | 2 (2.1) |
| Blurred vision/macular lesion | 2 (2.1) |
| Nausea/vertigo | 1 (1.06) |
| Anorexia | 1 (1.06) |
| Asthenia | 1 (1.06) |
| Erythromelalgia | 1 (1.06) |
| Cold sores | 1 (1.06) |
| Hypophosphatemia | 1 (1.06) |
| Pruritus | 1 (1.06) |
| Muscle cramps | 1 (1.06) |
| Mouth sores | 1 (1.06) |
| Myalgia | 1 (1.06) |
| Venous thromboembolism | 1 (1.06) |
| Acute myocardial infarction | 1 (1.06) |
| Variable . | n (%) . |
|---|---|
| Any adverse event | 94 (100) |
| Number of grade 3-4 events | 13 (13.8) |
| Diarrhea | 28 (29.8) |
| Hypertension | 21 (22.3) |
| Neutropenia grade 3-4 | 10 (10.6) |
| Headaches | 8 (8.5) |
| Hepatobiliary laboratory abnormalities | 7 (7.4) |
| Dyspepsia/epigastralgia | 4 (4.25) |
| Depression | 2 (2.1) |
| Blurred vision/macular lesion | 2 (2.1) |
| Nausea/vertigo | 1 (1.06) |
| Anorexia | 1 (1.06) |
| Asthenia | 1 (1.06) |
| Erythromelalgia | 1 (1.06) |
| Cold sores | 1 (1.06) |
| Hypophosphatemia | 1 (1.06) |
| Pruritus | 1 (1.06) |
| Muscle cramps | 1 (1.06) |
| Mouth sores | 1 (1.06) |
| Myalgia | 1 (1.06) |
| Venous thromboembolism | 1 (1.06) |
| Acute myocardial infarction | 1 (1.06) |